A client who received a blood transfusion 4 weeks ago now exhibits symptoms including fever, rash, diarrhea, and pancytopenia.
What complication might be responsible for these symptoms?
Delayed hemolytic reaction.
Graft-versus-host disease.
Transfusion-associated graft-versus-host disease (TA-GVHD)
Post-transfusion purpura.
The Correct Answer is C
Choice A rationale:
Delayed hemolytic reaction occurs more than 24 hours after a blood transfusion and is characterized by a drop in hemoglobin levels, jaundice, and a positive direct antiglobulin test (Coombs test)
It does not typically present with fever, rash, and pancytopenia, so it is not the best choice for the given symptoms.
Choice B rationale:
Graft-versus-host disease (GVHD) is a condition where donor T lymphocytes attack the recipient's tissues, often seen in bone marrow or stem cell transplant recipients.
While it can cause pancytopenia, it typically occurs within a few weeks of transplantation, not four weeks after a blood transfusion.
Therefore, it is less likely to be the cause in this scenario.
Choice C rationale:
Transfusion-associated graft-versus-host disease (TA-GVHD) occurs when viable T lymphocytes in the transfused blood attack the recipient's tissues.
Symptoms can include fever, rash, diarrhea, and pancytopenia.
TA-GVHD is a delayed complication of transfusion that typically presents about 1 to 6 weeks post-transfusion, making it the most likely cause of the symptoms described in the scenario.
Choice D rationale:
Post-transfusion purpura is a rare condition that occurs 5 to 12 days after a transfusion and is characterized by sudden severe thrombocytopenia (low platelet count) and bleeding, often in the form of purpura.
It does not typically present with fever, rash, and pancytopenia, so it is not the best choice for the given symptoms.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","E"]
Explanation
Choice A rationale:
Verify the patient's identification.
Rationale: Ensuring the correct patient is receiving the blood transfusion is a critical safety step.
Verifying the patient's identification helps prevent transfusion errors and ensures that the right blood product is administered to the right patient.
Choice B rationale:
Obtain informed consent.
Rationale: Obtaining informed consent is a necessary step before any medical procedure, including blood transfusions.
It ensures that the patient understands the risks, benefits, and alternatives to the transfusion and has the opportunity to ask questions and make an informed decision.
Choice E rationale:
Document the procedure accurately.
Rationale: Accurate documentation is essential for maintaining a complete record of the transfusion process.
It includes documenting the patient's identification, vital signs, the type and volume of blood product administered, any adverse reactions, and the patient's response to the transfusion.
This documentation serves as a legal and clinical record of the procedure.
Choice C rationale:
Monitor vital signs during the transfusion.
Rationale: While monitoring vital signs is important during a blood transfusion, it is not a responsibility before initiating the transfusion.
Vital sign monitoring occurs during the transfusion to detect any immediate adverse reactions or transfusion-related complications.
Choice D rationale:
Prepare the patient for an exchange transfusion.
Rationale: Preparing a patient for an exchange transfusion is not a nursing responsibility before initiating a routine blood transfusion.
Exchange transfusions are typically used for specific medical conditions, such as hemolytic disease of the newborn or sickle cell disease, and involve the removal and replacement of a large volume of blood.
Standard blood transfusions do not require this preparation.
For , fresh frozen plasma (FFP) is the most suitable blood product for increasing fibrinogen levels in a patient with hemophilia A.
For , the nursing responsibilities before initiating a blood transfusion include verifying the patient's identification, obtaining informed consent, and documenting the procedure accurately.
Monitoring vital signs is important but occurs during the transfusion, and preparing the patient for an exchange transfusion is not relevant to routine blood transfusions.
Correct Answer is B
Explanation
Choice A rationale:
"I'm feeling weak and dizzy." Rationale: Weakness and dizziness can be symptoms of anemia, which is often associated with low hemoglobin levels.
However, these symptoms alone are not a definitive indication for blood transfusion.
Other factors, such as the patient's overall clinical condition and the cause of the low hemoglobin, need to be considered.
Choice B rationale:
"My hemoglobin is 7 g/dL, so I need a transfusion." Rationale: This statement indicates that the patient is aware of their low hemoglobin level and believes they need a transfusion.
The hemoglobin level of 7 g/dL is a common threshold used as an indication for blood transfusion, especially in symptomatic patients.
This choice is correct because it aligns with the appropriate clinical indication for a transfusion based on the hemoglobin level.
Choice C rationale:
"I had orthopedic surgery yesterday." Rationale: While surgery can lead to blood loss, the statement alone does not provide sufficient information to determine if a transfusion is necessary.
The decision to transfuse blood should be based on the patient's hemoglobin level, overall clinical condition, and the extent of blood loss during surgery.
Choice D rationale:
"I have a stable cardiovascular disease." Rationale: The presence of stable cardiovascular disease is not directly related to the need for a blood transfusion based on a hemoglobin level of 7 g/dL.
The decision to transfuse should primarily be based on the patient's hemoglobin level and symptoms.
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