A client with a life-threatening infection is given a high dose of antibiotic on day 1 to quickly increase the serum drug concentration. On days 2-7, the client is given a lower dose of the same antibiotic to continue treating the infection. What term best describes the higher dose of antibiotic given to the client on day 1?
Definitive dose
Prophylactic dose
Maintenance dose
Loading dose
The Correct Answer is D
A. Definitive dose: A definitive dose refers to a dosage determined after identifying the specific pathogen and its drug sensitivity. It is not related to the initial high dose given to rapidly raise serum drug levels in the body.
B. Prophylactic dose: A prophylactic dose is administered to prevent infection, not to treat an existing one. It is typically lower and given before exposure or surgery, unlike the large therapeutic dose described in this scenario.
C. Maintenance dose: A maintenance dose is a smaller, ongoing dose used to maintain a drug’s effective concentration after the initial therapeutic level has been reached. In this case, the lower doses given from days 2–7 represent the maintenance phase.
D. Loading dose: A loading dose is a higher initial dose given to rapidly achieve a therapeutic drug concentration in the bloodstream, especially when immediate drug action is needed. The high dose given on day 1 fits this definition precisely.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Improve mood and reduce hallucinations: Cannabinoids are not primarily prescribed to manage mood or hallucinations. At high doses, they may cause euphoria or perceptual changes rather than reduce them .
B. Stomach acid reduction and improved digestion: Cannabinoids do not act on gastric acid secretion or promote digestion. Drugs such as proton pump inhibitors or H2 blockers are used for acid-related disorders, not cannabinoids.
C. Nausea reduction and appetite stimulation: Dronabinol and other cannabinoids are used to manage chemotherapy-induced nausea and vomiting by acting on the central nervous system’s vomiting center. They also stimulate appetite in patients experiencing anorexia or cachexia.
D. Improve memory and attention: Cannabinoids can actually impair memory and attention due to their effects on the central nervous system. Therefore, they are not prescribed for cognitive enhancement but rather for symptom relief in select clinical conditions.
Correct Answer is A
Explanation
A. Dilates blood vessels to increase blood flow: Ginkgo biloba primarily works by improving circulation through vasodilation and reducing platelet aggregation. Enhanced cerebral blood flow is thought to support memory, cognition, and overall brain function.
B. Stimulates the effects of the neurotransmitter dopamine: Dopamine stimulation is associated with medications used for Parkinson’s disease, such as levodopa. Ginkgo biloba does not act on dopamine receptors or pathways and therefore does not produce dopaminergic effects.
C. Mimics the effect of the hormone estrogen: Phytoestrogenic effects are linked to herbs like black cohosh or soy isoflavones. Ginkgo biloba does not mimic estrogenic activity or influence hormonal balance.
D. Enhances the effects of the neurotransmitter GABA: Herbs such as valerian root and kava act on GABA receptors to promote relaxation. Ginkgo biloba does not enhance GABA activity; its benefits stem from vascular and antioxidant mechanisms rather than sedative properties.
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