Which factors affect medication absorption? (Select all that apply.)
The dosage form of the medication.
The dosing frequency of the medication.
Route of medication administration.
The health of the client's liver.
The potency of the medication.
Correct Answer : A,C,D
A. The dosage form of the medication: The formulation whether tablet, capsule, liquid, or injection directly influences how quickly and efficiently a drug dissolves and is absorbed. Liquid and injectable forms are generally absorbed faster than solid oral forms due to reduced dissolution time.
B. The dosing frequency of the medication: Dosing frequency affects how often a drug is administered and its plasma concentration over time but does not influence the rate or extent of absorption for each individual dose. It relates more to maintaining therapeutic levels than initial absorption.
C. Route of medication administration: The route determines how a drug enters the body and whether it must pass through barriers like the gastrointestinal tract or skin. For instance, intravenous routes provide immediate absorption, while oral routes are slower and influenced by digestion.
D. The health of the client’s liver: Liver health can indirectly affect absorption by altering metabolism during the first-pass effect. If hepatic function is impaired, more of the drug may reach systemic circulation unmetabolized, changing the effective absorption profile.
E. The potency of the medication: Potency describes the amount of drug needed to achieve a desired effect, not how well it is absorbed. A potent drug may still have poor absorption if its formulation or route is not optimal.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Has several contraindications: An ideal drug should have minimal contraindications to ensure it can be safely used by most patients. Multiple contraindications increase the risk of adverse reactions and limit the drug’s clinical usefulness.
B. Effective at low doses: High potency and effectiveness at low doses are desirable characteristics of an ideal drug. It allows therapeutic effects to be achieved with minimal drug exposure, reducing toxicity risk and improving patient safety.
C. Only available as an injection: Ideally, a drug should be easy to administer, and oral forms are generally preferred for convenience and patient compliance. Limiting availability to injections reduces accessibility and increases discomfort for patients.
D. Frequent dosing schedule: An ideal drug should have a long duration of action to reduce dosing frequency. Fewer doses improve adherence, convenience, and consistency in maintaining therapeutic drug levels.
Correct Answer is C
Explanation
A. The time it takes for the medication to begin having a therapeutic effect: This describes the onset of action, which is the time between drug administration and the first noticeable therapeutic effect.
B. The drug concentration at which the client begins to experience toxicity: This describes the toxic concentration, which indicates when drug levels rise high enough to cause harmful effects. It does not reflect the normal highest concentration of the drug in the bloodstream.
C. The highest concentration of drug that is achieved in the client's blood: The peak level refers to the maximum plasma concentration reached after a dose is administered and absorbed. Monitoring peak levels is important for drugs with narrow therapeutic ranges to avoid toxicity.
D. The drug concentration at which a therapeutic effect will begin to occur: This describes the minimum effective concentration (MEC), which is the lowest drug level needed to produce the desired effect.
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