A group of football players is taking oral griseofulvin for tinea pedis.
What should the school nurse caution them to avoid?
Citrus fruit and juice.
Eating shellfish.
Alcohol consumption.
Taking corticosteroids.
The Correct Answer is C
Choice A rationale
There is no known or documented significant drug-food interaction between griseofulvin and citrus fruits or juice. Griseofulvin absorption is actually enhanced by a high-fat meal. The biological mechanism of action for griseofulvin does not involve competition with compounds found in citrus.
Choice B rationale
Shellfish allergies are a common food allergy, but there is no specific interaction between griseofulvin, an antifungal, and shellfish consumption. Griseofulvin's mechanism of action involves disrupting fungal mitosis, which is not affected by dietary intake of shellfish.
Choice C rationale
Alcohol consumption while taking griseofulvin can lead to a disulfiram-like reaction, which is a severe adverse response. This reaction is characterized by flushing, headache, nausea, vomiting, and a rapid heartbeat. The exact mechanism is not fully understood, but it is a significant and dangerous interaction.
Choice D rationale
Griseofulvin is an antifungal medication, while corticosteroids are anti-inflammatory and immunosuppressive agents. There is no known direct pharmacological interaction between these two drug classes. Taking them concurrently is not contraindicated, although they treat different conditions.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
While occlusive agents like Vaseline can smother lice, this method is messy and generally not as effective as targeted pediculicides. It mainly suffocates the live lice but does not consistently eliminate the nits (eggs), which are tightly attached to the hair shaft and must be removed to prevent reinfestation.
Choice B rationale
A soda-vinegar solution has no proven efficacy in eradicating lice. The acetic acid in vinegar can help loosen the glue-like substance that attaches nits to the hair shaft, but it is not a standalone treatment. Baking soda does not have any scientific basis for being effective against pediculosis.
Choice C rationale
A vinegar-water solution, specifically the acetic acid in vinegar, helps to dissolve the proteinaceous cement substance that glues nits to the hair shaft. This makes the nits easier to remove with a fine-toothed nit comb, which is a crucial step in the eradication process to prevent the hatching of new lice.
Choice D rationale
Dish detergents are not formulated to be effective against lice and can be harsh on the scalp, causing irritation. They lack the specific neurotoxic agents or suffocation properties found in approved pediculicide shampoos that are designed to kill lice and their eggs. This method is ineffective and potentially harmful. .
Correct Answer is B
Explanation
Choice A rationale
Ambulating with assistance is not an immediate indicator of a positive outcome for a client with a DVT. Ambulation is often contraindicated in the initial stages of treatment to prevent a pulmonary embolism. Therefore, this assessment does not reflect a primary outcome of DVT management, which focuses on preventing complications and resolving the clot.
Choice B rationale
An oxygen saturation of 98% is a critical indicator that the client has not developed a pulmonary embolism, a serious and life-threatening complication of DVT. This outcome demonstrates that the thrombus has not dislodged and traveled to the lungs, obstructing gas exchange. Normal oxygen saturation levels range from 95% to 100%.
Choice C rationale
While pain reduction is an important aspect of care, a pain score of 2/10 after medication is a temporary relief measure and does not represent a definitive outcome for DVT. The primary goal is to prevent a pulmonary embolism and resolve the thrombus, and pain control is a supportive measure in achieving that goal.
Choice D rationale
Verbalizing risk factors indicates that the client has received education, which is an important intervention. However, it is an educational outcome, not a physiological one. It does not provide direct evidence that the DVT is resolving or that the client is free from the most serious complication of the disease, a pulmonary embolism.
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