A group of football players is taking oral griseofulvin for tinea pedis.
What should the school nurse caution them to avoid?
Citrus fruit and juice.
Eating shellfish.
Alcohol consumption.
Taking corticosteroids.
The Correct Answer is C
Choice A rationale
There is no known or documented significant drug-food interaction between griseofulvin and citrus fruits or juice. Griseofulvin absorption is actually enhanced by a high-fat meal. The biological mechanism of action for griseofulvin does not involve competition with compounds found in citrus.
Choice B rationale
Shellfish allergies are a common food allergy, but there is no specific interaction between griseofulvin, an antifungal, and shellfish consumption. Griseofulvin's mechanism of action involves disrupting fungal mitosis, which is not affected by dietary intake of shellfish.
Choice C rationale
Alcohol consumption while taking griseofulvin can lead to a disulfiram-like reaction, which is a severe adverse response. This reaction is characterized by flushing, headache, nausea, vomiting, and a rapid heartbeat. The exact mechanism is not fully understood, but it is a significant and dangerous interaction.
Choice D rationale
Griseofulvin is an antifungal medication, while corticosteroids are anti-inflammatory and immunosuppressive agents. There is no known direct pharmacological interaction between these two drug classes. Taking them concurrently is not contraindicated, although they treat different conditions.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Peripheral arterial disease causes reduced blood flow to the extremities, making them highly susceptible to thermal injury. A heating pad can cause a severe burn because the compromised circulation prevents adequate heat dissipation, and the impaired sensation often associated with PAD means the client may not feel the excessive heat.
Choice B rationale
Crossing legs compresses the popliteal artery and other vessels, further impeding already compromised arterial blood flow to the lower extremities. This action increases resistance and reduces tissue perfusion, exacerbating the ischemic symptoms and potentially worsening the disease progression.
Choice C rationale
Wearing warm, heavy socks is a safe and effective way to promote warmth and vasodilation in the feet without the risk of burns. By maintaining warmth, it helps to prevent vasospasm and promotes better collateral blood flow to the affected extremities, improving comfort and circulation.
Choice D rationale
Smoking causes intense vasoconstriction through nicotine's effects on the sympathetic nervous system and damages the endothelial lining of blood vessels, accelerating the atherosclerotic process. Quitting smoking is the single most effective intervention to slow the progression of PAD and reduce cardiovascular risk.
Correct Answer is C
Explanation
Choice A rationale
While occlusive agents like Vaseline can smother lice, this method is messy and generally not as effective as targeted pediculicides. It mainly suffocates the live lice but does not consistently eliminate the nits (eggs), which are tightly attached to the hair shaft and must be removed to prevent reinfestation.
Choice B rationale
A soda-vinegar solution has no proven efficacy in eradicating lice. The acetic acid in vinegar can help loosen the glue-like substance that attaches nits to the hair shaft, but it is not a standalone treatment. Baking soda does not have any scientific basis for being effective against pediculosis.
Choice C rationale
A vinegar-water solution, specifically the acetic acid in vinegar, helps to dissolve the proteinaceous cement substance that glues nits to the hair shaft. This makes the nits easier to remove with a fine-toothed nit comb, which is a crucial step in the eradication process to prevent the hatching of new lice.
Choice D rationale
Dish detergents are not formulated to be effective against lice and can be harsh on the scalp, causing irritation. They lack the specific neurotoxic agents or suffocation properties found in approved pediculicide shampoos that are designed to kill lice and their eggs. This method is ineffective and potentially harmful. .
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