A long-term complication sees in Thalassemia major are associated to which of the following?

Fatigue

Deferoxamine usage

Immunosuppressive therapy

Hemochromatosis/Hemosiderosis

Answer and Explanation

The Correct Answer is D

Option A, "Fatigue," is a symptom of anemia but is not a long-term complication associated with Thalassemia major.

Option B, "Deferoxamine usage," is a treatment to manage iron overload and not a complication associated with Thalassemia major.

Option C, "Immunosuppressive therapy," is not typically used to manage Thalassemia major and is not a long-term complication but rather a potential treatment for certain cases of thalassemia.

Option D. Hemochromatosis/Hemosiderosis

Thalassemia major is a genetic disorder that results in the body's inability to produce enough hemoglobin, leading to severe anemia.

To manage this condition, frequent blood transfusions are required, which can lead to iron overload in the body. Excess iron gets deposited in various organs and tissues, causing damage.

Hemochromatosis or hemosiderosis is a condition characterized by the accumulation of iron in organs like the liver, heart, and endocrine glands, which can result from repeated blood transfusions.

The complications associated with iron overload include liver damage, heart problems, diabetes, and more. Treatment with iron chelating agents like deferoxamine is often necessary to remove excess iron from the body.

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Correct Answer is B

Explanation

A. "The body's response to gluten causes the intestine to become more porous and hang on to more of the fat-soluble vitamins, leading to vitamin toxicity." This answer is not accurate. The issue in celiac disease is malabsorption, not vitamin toxicity.

B. "The body's response to gluten causes damage to the mucosal cells in the intestines leading to absorption problems."

Celiac disease is an autoimmune disorder in which the ingestion of gluten (a protein found in wheat, barley, and rye) leads to damage of the mucosal cells in the small intestine. This damage, in turn, can lead to malabsorption of essential nutrients, including vitamins, minerals, and other important components of the diet. It is important for individuals with celiac disease to avoid gluten-containing foods to prevent ongoing damage to the intestinal mucosa and improve nutrient absorption.

C. "The body's response to consumption of anything containing gluten is to create special cells called villi, which leads to more diarrhea." This statement is not accurate. Celiac disease leads to damage to the villi (finger-like projections) in the small intestine, not the creation of special cells. It can lead to diarrhea but is not the primary cause.

D. "The body's response to gluten causes damage to the mucosal cells, leading to malabsorption of water and hard, constipated stools." This response is not accurate. Celiac disease is more commonly associated with diarrhea and malabsorption, not constipation and malabsorption of water.

A. Place the infant in reverse Trendelenburg position B. Place the infant in the knee to chest position C. Take the infant's blood pressure in all extremities D. Notify the Physician

Correct Answer is C

Explanation

Option A (Place the infant in reverse Trendelenburg position) and option B (Place the infant in the knee to chest position) are not the immediate actions to address this situation. While these positions might be used in specific situations, assessing blood pressure is more appropriate in this context to evaluate for potential vascular issues.

Option C. Take the infant's blood pressure in all extremities.

In an infant with weaker femoral pulses compared to the brachial and radial pulses, there might be a concern about coarctation of the aorta (a narrowing of the aorta), which can affect blood flow to the lower extremities. To confirm this and assess for potential issues, taking blood pressure measurements in all four extremities is crucial. This comparison can help identify pressure differentials between the upper and lower extremities, which is a hallmark sign of coarctation of the aorta.

Option D (Notify the Physician) is generally a good step, but taking the blood pressure in all extremities should be done first to provide comprehensive information for the physician when discussing the infant's condition.

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A long-term complication sees in Thalassemia major are associated to which of the following?

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Naxlex Comprehensive Predictor Exams

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Explanation

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Correct Answer is C

Explanation

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