A nurse in an influenza clinic is collecting data from four clients. Which of the following clients should the nurse identify as having a contraindication for receiving the live attenuated form of the influenza vaccine?

D. One of the primary requirements of the iPledge program for sexually active females of childbearing potential is the use of two forms of contraception simultaneously, beginning one month before starting isotretinoin therapy, throughout therapy, and for one month after discontinuation of therapy. This is to ensure effective contraception and prevent pregnancy due to the teratogenic effects of isotretinoin.
A. While mammograms are important screening tests for breast cancer, they are not a requirement of the iPledge program for female clients receiving isotretinoin.
B. Papanicolaou (Pap) tests, which screen for cervical cancer, are not a requirement of the iPledge program. However, sexually active females of childbearing potential must have monthly pregnancy tests and must agree to use two forms of contraception simultaneously during isotretinoin therapy.
C. There is no requirement for clients to take a daily supplement of vitamin A prior to initiating isotretinoin therapy as part of the iPledge program.

A. Increased respiratory rate is a sign that naloxone is effectively reversing opioid-induced respiratory depression. Opioids can suppress the respiratory drive, leading to hypoventilation or respiratory arrest. Naloxone works by competitively binding to opioid receptors and displacing opioids, thereby restoring normal respiratory function.
B. Increased temperature is not a direct effect of naloxone administration. Naloxone primarily reverses the central nervous system depressant effects of opioids, including respiratory depression and sedation, rather than affecting body temperature.
C. Naloxone does not directly affect pain perception. Its primary action is to reverse the respiratory depression and central nervous system depression caused by opioids. While the client may experience pain relief indirectly as a result of improved respiratory function and consciousness, naloxone itself does not directly reduce pain.
D. Decreased blood pressure is not a direct effect of naloxone administration. Naloxone primarily reverses the respiratory and central nervous system depressant effects of opioids, rather than affecting blood pressure directly.