A nurse is caring for a client diagnosed with acute myeloid leukemia (AML). Which statement best describes the pathophysiology of AML?
"AML is characterized by the overproduction of immature lymphocytes, leading to bone marrow failure."
"In AML, abnormal proliferation of red blood cells causes decreased oxygen-carrying capacity in the blood."
"Genetic mutations in the myeloid stem cells lead to uncontrolled growth of abnormal myeloid cells in AML."
"AML is caused by the abnormal growth of plasma cells, leading to the production of abnormal antibodies."
The Correct Answer is C
A) This choice is incorrect because AML is not characterized by the overproduction of immature lymphocytes. It involves the uncontrolled proliferation of abnormal myeloid cells in the bone marrow.
B) This choice is incorrect because AML does not cause abnormal proliferation of red blood cells. Anemia may occur as a result of AML due to the displacement of normal blood-forming cells in the bone marrow.
C) This choice is correct. AML is a type of leukemia that arises from genetic mutations in the myeloid stem cells. These mutations lead to uncontrolled growth and accumulation of abnormal myeloid cells, including granulocytes, monocytes, and platelets.
D) This choice is incorrect because the abnormal growth of plasma cells leading to the production of abnormal antibodies is characteristic of multiple myeloma, not AML.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A) This choice is incorrect because gentle stretching exercises are generally safe and do not significantly increase the risk of bleeding in clients with low platelet counts.
B) This choice is incorrect because deep vein thrombosis (DVT) prophylaxis, such as leg exercises and anti-embolism stockings, is essential to prevent blood clots but is not directly related to bleeding risk.
C) This choice is incorrect because using a soft-bristled toothbrush helps prevent gum bleeding and trauma to the oral mucosa but does not address the risk of bleeding from other areas.
D) This choice is correct. Vigorous nose blowing can lead to trauma to the nasal mucosa and increase the risk of bleeding, especially in clients with low platelet counts who are prone to bleeding episodes.
Correct Answer is C
Explanation
A) This choice is incorrect because stem cell transplantation is not the primary treatment for all cases of chronic myeloid leukemia (CML). It may be considered in certain cases, but targeted therapy is the standard first-line treatment for most patients with CML.
B) This choice is incorrect because while chemotherapy and radiation therapy are used in some leukemia treatments, they are not the main treatments for CML. Targeted therapy with tyrosine kinase inhibitors is the standard approach for CML management.
C) This choice is correct. The mainstay of treatment for chronic myeloid leukemia (CML) is targeted therapy with tyrosine kinase inhibitors (TKIs). TKIs are oral medications that specifically target the abnormal protein produced by the BCR-ABL gene, which drives the overproduction of white blood cells in CML. These medications are highly effective and have revolutionized the treatment of CML, leading to improved outcomes for many patients.
D) This choice is incorrect because watchful waiting and supportive care may be considered for certain low-risk or asymptomatic cases of CML, but it is not the primary treatment approach. Targeted therapy with TKIs is the standard treatment for most patients with CML.
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