A nurse is caring for a client diagnosed with acute myeloid leukemia (AML). Which statement best describes the pathophysiology of AML?
"AML is characterized by the overproduction of immature lymphocytes, leading to bone marrow failure."
"In AML, abnormal proliferation of red blood cells causes decreased oxygen-carrying capacity in the blood."
"Genetic mutations in the myeloid stem cells lead to uncontrolled growth of abnormal myeloid cells in AML."
"AML is caused by the abnormal growth of plasma cells, leading to the production of abnormal antibodies."
The Correct Answer is C
A) This choice is incorrect because AML is not characterized by the overproduction of immature lymphocytes. It involves the uncontrolled proliferation of abnormal myeloid cells in the bone marrow.
B) This choice is incorrect because AML does not cause abnormal proliferation of red blood cells. Anemia may occur as a result of AML due to the displacement of normal blood-forming cells in the bone marrow.
C) This choice is correct. AML is a type of leukemia that arises from genetic mutations in the myeloid stem cells. These mutations lead to uncontrolled growth and accumulation of abnormal myeloid cells, including granulocytes, monocytes, and platelets.
D) This choice is incorrect because the abnormal growth of plasma cells leading to the production of abnormal antibodies is characteristic of multiple myeloma, not AML.
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Related Questions
Correct Answer is C
Explanation
A) This choice is incorrect because increased platelet production would not lead to easy bruising and petechiae. It would, in fact, improve clotting abilities.
B) This choice is incorrect because overproduction of red blood cells would not directly cause easy bruising and petechiae. It may lead to symptoms like fatigue and pallor.
C) This choice is correct. Easy bruising and petechiae are common in leukemia due to a deficiency of platelets and impaired clotting factors in the blood. Leukemia can lead to decreased platelet production and clotting abnormalities, resulting in easy bleeding and bruising.
D) This choice is incorrect because a deficiency of white blood cells would not directly cause easy bruising and petechiae. It might lead to an increased risk of infections.
Correct Answer is D
Explanation
A) This choice is incorrect because mild redness and tenderness at the IV site are common findings and may indicate a local inflammatory response to the IV infusion.
B) This choice is incorrect because a temperature of 99.8°F (37.7°C) is slightly elevated but not a critical finding. The client's healthcare provider should be notified if the temperature is significantly elevated or if other symptoms are present.
C) This choice is incorrect because a small amount of blood in the IV tubing may be due to a minor infiltration or a common occurrence during IV administration. However, the nurse should monitor the IV site and flow rate closely.
D) This choice is correct. Crackles and decreased breath sounds on auscultation may indicate fluid overload or pulmonary edema, which could be a severe complication of IV chemotherapy. The healthcare provider should be notified immediately to assess the client's respiratory status and provide appropriate intervention.
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