A nurse is caring for a client diagnosed with acute myeloid leukemia (AML). Which statement best describes the pathophysiology of AML?
"AML is characterized by the overproduction of immature lymphocytes, leading to bone marrow failure."
"In AML, abnormal proliferation of red blood cells causes decreased oxygen-carrying capacity in the blood."
"Genetic mutations in the myeloid stem cells lead to uncontrolled growth of abnormal myeloid cells in AML."
"AML is caused by the abnormal growth of plasma cells, leading to the production of abnormal antibodies."
The Correct Answer is C
A) This choice is incorrect because AML is not characterized by the overproduction of immature lymphocytes. It involves the uncontrolled proliferation of abnormal myeloid cells in the bone marrow.
B) This choice is incorrect because AML does not cause abnormal proliferation of red blood cells. Anemia may occur as a result of AML due to the displacement of normal blood-forming cells in the bone marrow.
C) This choice is correct. AML is a type of leukemia that arises from genetic mutations in the myeloid stem cells. These mutations lead to uncontrolled growth and accumulation of abnormal myeloid cells, including granulocytes, monocytes, and platelets.
D) This choice is incorrect because the abnormal growth of plasma cells leading to the production of abnormal antibodies is characteristic of multiple myeloma, not AML.
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Correct Answer is B
Explanation
A) This choice is incorrect because leukemia is not primarily caused by exposure to infectious agents. While some viral infections may increase the risk of certain types of leukemia, infectious agents are not the main cause.
B) This choice is correct. The exact cause of leukemia is not fully understood, and it can vary among individuals. It is believed to result from a combination of genetic mutations and environmental factors, but no single cause has been identified for all cases.
C) This choice is incorrect because while genetic mutations can play a role in the development of some types of leukemia, they are not the only cause. Environmental factors and other unknown factors also contribute to leukemia.
D) This choice is incorrect because while environmental toxins and pollution may be risk factors for some individuals, they are not the leading factors in all cases of leukemia.
Correct Answer is B
Explanation
A) This choice is incorrect because chemotherapy for acute lymphocytic leukemia (ALL) usually lasts much longer than a few weeks. ALL treatment consists of several phases, and the overall duration can extend over several years.
B) This choice is correct. Treatment for acute lymphocytic leukemia (ALL) typically involves multiple phases, including induction, consolidation, and maintenance therapy. The induction phase aims to achieve remission, the consolidation phase aims to eliminate any remaining cancer cells, and the maintenance phase aims to prevent relapse and keep the leukemia in remission. Overall, the treatment can extend over several years, depending on the client's response to therapy and risk factors.
C) This choice is incorrect because it does not accurately reflect the standard treatment approach for ALL. Clients with ALL do not typically switch from chemotherapy to radiation therapy after a few days.
D) This choice is incorrect because ALL treatment typically involves multiple rounds of chemotherapy, not just a single round. The goal is to achieve long-term remission and prevent relapse, which requires a more comprehensive treatment approach over an extended period.
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