A nurse is caring for a client who is receiving warfarin therapy. Which of the following medications should the nurse expect to administer if the client develops bleeding as an adverse effect of the medication? (Select all that apply.)
Vitamin K
Fresh frozen plasma
Protamine sulfate
Factor IX complex concentrate E.
Correct Answer : A,B
Vitamin K and fresh frozen plasma are both used to reverse the effects of warfarin and stop the bleeding. Vitamin K is a cofactor for the synthesis of clotting factors in the liver, and fresh frozen plasma contains clotting factors that can replenish the depleted ones.
Choice C is wrong because protamine sulfate is an antidote for heparin, not warfarin. Choice D is wrong because factor IX complex concentrate is used to treat hemophilia B, not warfarin-induced bleeding.
Choice E is wrong because tranexamic acid is an antifibrinolytic agent that prevents the breakdown of clots, but does not reverse the effects of warfarin.
Normal ranges for PT (prothrombin time) and INR (international normalized ratio) are 11 to 13.5 seconds and 0.8 to 1.2, respectively. Warfarin therapy aims to prolong the PT and INR to prevent clot formation.
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Related Questions
Correct Answer is C
Explanation
Enoxaparin is an anticoagulant that helps prevent the formation of blood clots in patients with DVT.It can also cause bleeding or other side effects, so patients should monitor for any signs of bleeding and report them to their provider.
Choice A is wrong because aspirin is not contraindicated with enoxaparin.Aspirin is also an antiplatelet agent that can prevent thrombosis, and it may be used in combination with enoxaparin for certain indications, such as acute coronary syndrome.
Choice B is wrong because ibuprofen is not contraindicated with enoxaparin.Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce pain and inflammation, and it may be used with enoxaparin for certain conditions, such as arthritis.However, NSAIDs can also increase the risk of bleeding, so patients should use them with caution and inform their provider if they are taking them.
Choice D is wrong because enoxaparin does not need to be taken with food.Enoxaparin is given by subcutaneous injection, so food does not affect its absorption or efficacy.Patients should follow the instructions on how to inject enoxaparin properly and store it at room temperature.
Correct Answer is C
Explanation
“I should report any unusual bleeding or bruising to my provider.” This statement indicates that the client understands that warfarin is an anticoagulant that can increase the risk of bleeding and that any signs of bleeding should be reported promptly.Warfarin works by inhibiting the synthesis of vitamin K-dependent clotting factors, so the client should monitor their intake of vitamin K, but not avoid it completely.Warfarin can be taken with or without food, so choice B is not correct.
Aspirin is also an anticoagulant and can increase the risk of bleeding when taken with warfarin, so the client should avoid taking it unless prescribed by the provider
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