A nurse is caring for a patient who received a blood transfusion 10 days ago.
The patient presents with symptoms of fever, jaundice, hemoglobinuria, and a positive Coombs test.
What complication is the patient likely experiencing?
Delayed hemolytic reaction.
Transfusion-associated graft-versus-host disease (TA-GVHD)
Post-transfusion purpura.
Transfusion-related immunomodulation (TRIM)
The Correct Answer is A
Choice A rationale:
Delayed hemolytic reactions occur several days after a blood transfusion and are characterized by symptoms like fever, jaundice, hemoglobinuria, and a positive Coombs test.
This matches the patient's presentation described in the question.
Choice B rationale:
Transfusion-associated graft-versus-host disease (TA-GVHD) typically presents with fever, rash, diarrhea, and liver dysfunction.
It is a rare but severe complication that occurs when the donor's lymphocytes attack the recipient's tissues.
Choice C rationale:
Post-transfusion purpura is a rare condition characterized by severe thrombocytopenia (low platelet count) that occurs a week or more after a blood transfusion.
It does not match the symptoms described in the question.
Choice D rationale:
Transfusion-related immunomodulation (TRIM) is a theoretical concept and not a recognized clinical entity.
It is not associated with the specific symptoms mentioned in the question.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale:
AB+ blood type contains both A and B antigens as well as the Rh antigen (positive)
Blood type O+ has neither A nor B antigens but does have the Rh antigen.
Therefore, AB+ blood cannot be safely transfused to a client with blood type O+ as it would lead to a mismatch in ABO compatibility.
Choice B rationale:
O- blood type is the universal donor for red blood cell transfusions.
It lacks both A and B antigens as well as the Rh antigen, making it compatible with all other blood types.
Since the client in question has blood type O+, which is Rh-positive, O- blood can be safely transfused without any ABO or Rh incompatibility.
Choice C rationale:
A+ blood type contains A antigens and the Rh antigen (positive)
Blood type O+ lacks A antigens but does have the Rh antigen.
Therefore, A+ blood is not compatible with O+ blood due to ABO incompatibility.
Choice D rationale:
B+ blood type contains B antigens and the Rh antigen (positive)
Blood type O+ lacks B antigens but does have the Rh antigen.
Therefore, B+ blood is not compatible with O+ blood due to ABO incompatibility.
Correct Answer is A
Explanation
Choice A rationale:
Delayed hemolytic reactions occur several days after a blood transfusion and are characterized by symptoms like fever, jaundice, hemoglobinuria, and a positive Coombs test.
This matches the patient's presentation described in the question.
Choice B rationale:
Transfusion-associated graft-versus-host disease (TA-GVHD) typically presents with fever, rash, diarrhea, and liver dysfunction.
It is a rare but severe complication that occurs when the donor's lymphocytes attack the recipient's tissues.
Choice C rationale:
Post-transfusion purpura is a rare condition characterized by severe thrombocytopenia (low platelet count) that occurs a week or more after a blood transfusion.
It does not match the symptoms described in the question.
Choice D rationale:
Transfusion-related immunomodulation (TRIM) is a theoretical concept and not a recognized clinical entity.
It is not associated with the specific symptoms mentioned in the question.
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