A nurse is caring for client who is taking lisinopril (ACE inhibitor). Which of the following outcomes indicates a therapeutic effect of the medication?

A) Granulation tissue forming at the bottom of the wound bed:
Granulation tissue typically forms in wounds that heal by secondary intention. This type of healing occurs when the wound edges are not approximated (e.g., a large or open wound), and new tissue must form to fill the gap. In primary intention healing, the wound edges are well approximated, and granulation tissue is not the hallmark of the healing process, although some may appear early on.

B) Healing of the wound is prolonged:
Wounds healing by primary intention generally heal more quickly than those healing by secondary intention. In primary intention, the wound edges are approximated with sutures, staples, or adhesive, allowing for a faster and more efficient healing process. Therefore, prolonged healing is not expected with primary intention]

C) Skin edges of the wound are sutured closed:
This is the correct finding for a wound healing by primary intention. Primary intention healing occurs when the wound edges are brought together (approximated) and secured with sutures, staples, or adhesive strips. This method promotes faster healing and minimal scarring because the tissue is directly aligned.

D) Wound is contaminated at the time of injury:
Wounds that heal by primary intention are generally clean and not contaminated. If a wound is contaminated or infected at the time of injury, it is more likely to heal by secondary intention, where the tissue must fill in from the base upwards, which takes longer and may result in more scarring.

A) "Break needles on syringes before disposal":
Breaking needles before disposal is not a safe practice because it increases the risk of injury to staff during disposal. Needles should be disposed of intact in designated sharps containers to prevent injury. Tampering with used needles or syringes could expose staff to bloodborne pathogens.

B) "Use two hands to recap a needle after administering a medication":
The use of two hands to recap a needle is a high-risk behavior and should be avoided. The proper procedure is to never recap a needle after use. If recapping is absolutely necessary, a one-handed technique using the cap or a mechanical device should be employed to reduce the risk of needlestick injuries. The best practice is to dispose of the needle immediately in a sharps container.

C) "Dispose of used razors in wastebaskets":
Used razors should never be disposed of in wastebaskets, as this poses a significant risk of injury to waste management personnel. Razors, like needles and other sharp objects, should be placed in a designated sharps container. These containers are puncture-resistant and provide a safe environment for the disposal of used sharp items.

D) "Replace sharps containers when they are 3/4 full":
Sharps containers should be replaced when they are 3/4 full to prevent overfilling, which increases the risk of needlestick injuries. Overfilled containers can also make it difficult to dispose of new sharps safely. It is essential to follow institutional guidelines for the proper disposal of sharps and ensure that containers are replaced in a timely manner to maintain a safe environment.