A nurse is collecting data from a client who is taking dimenhydrinate to treat motion sickness. Which of the following findings is an adverse effect of this medication?

Drowsiness

Hypertension

Polyuria

Dependent edema

Answer and Explanation

The Correct Answer is A

A. Drowsiness. Dimenhydrinate is an antihistamine that works by blocking histamine and acetylcholine receptors in the brain to prevent nausea and vomiting. A common adverse effect is drowsiness due to its sedative properties, which can impair alertness and coordination. Clients should be advised to avoid activities requiring mental alertness, such as driving, until they understand how the medication affects them.

B. Hypertension. Dimenhydrinate does not typically cause hypertension. Instead, it may lead to mild hypotension due to its sedative and anticholinergic effects. Clients with pre-existing hypertension should still monitor their blood pressure, but significant increases are uncommon.

C. Polyuria. Increased urination is not associated with dimenhydrinate use. Antihistamines, including dimenhydrinate, have anticholinergic properties, which can lead to urinary retention rather than increased urine output. Clients experiencing difficulty urinating should report this to their healthcare provider.

D. Dependent edema. Dimenhydrinate does not cause fluid retention or edema. Medications that contribute to edema typically involve hormonal, cardiovascular, or kidney-related effects, which are not mechanisms of dimenhydrinate. If a client develops unexplained edema, other underlying conditions should be investigated.

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Correct Answer is B

Explanation

A. Promethazine. Promethazine is an antihistamine used to treat nausea, vomiting, and allergic reactions. It does not have antihypertensive properties and does not lower blood pressure. Instead, it has sedative effects and is commonly used for motion sickness or as a preoperative medication.

B. Amlodipine. Amlodipine is a calcium channel blocker that lowers blood pressure by relaxing blood vessels and improving blood flow. It is commonly prescribed for hypertension and angina, as it reduces vascular resistance and decreases the workload on the heart. Clients taking amlodipine should be monitored for hypotension, edema, and dizziness.

C. Fluconazole. Fluconazole is an antifungal medication used to treat fungal infections such as candidiasis. It does not affect blood pressure regulation and is not used for managing hypertension. However, it can interact with certain medications, so monitoring for drug interactions is important.

D. Phenazopyridine. Phenazopyridine is a urinary analgesic used to relieve symptoms of urinary tract infections (UTIs), such as burning and pain during urination. It does not lower blood pressure and has no effect on cardiovascular function. Clients should be advised that this medication can cause orange discoloration of the urine.

A. Bleeding B. Dysrhythmias C. Dizziness D. Jaundice

Correct Answer is A

Explanation

A. Bleeding. Cefotetan, a second-generation cephalosporin, can interfere with vitamin K metabolism, leading to a decreased ability to form blood clots. When combined with NSAIDs, which have an antiplatelet effect, the risk of bleeding increases. Clients taking both medications should be monitored for bruising, prolonged bleeding, or signs of gastrointestinal hemorrhage such as black, tarry stools.

B. Dysrhythmias. Cefotetan and NSAIDs do not have significant cardiac effects that would lead to dysrhythmias. Some antibiotics, such as macrolides and fluoroquinolones, can cause QT prolongation, but cefotetan does not affect cardiac conduction.

C. Dizziness. While NSAIDs can sometimes cause dizziness as a side effect, this is not a significant interaction between cefotetan and NSAIDs. Cefotetan does not commonly cause dizziness unless associated with an allergic reaction or severe hypotension due to an adverse effect.

D. Jaundice. Cefotetan is metabolized by the liver, but it is not highly hepatotoxic and does not commonly cause jaundice. NSAIDs, when used long-term or in high doses, may contribute to liver dysfunction, but this is not a primary concern in the interaction between these two medications.

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A nurse is collecting data from a client who is taking dimenhydrinate to treat motion sickness. Which of the following findings is an adverse effect of this medication?

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