A nurse is discussing the factors that can affect Alpha-fetoprotein Test (AFP) results with a pregnant client.
Which factor should the nurse mention?
Maternal weight.
Fetal heart rate.
Gestational age.
Placental function.
The Correct Answer is C
The level of AFP in a pregnant woman’s blood depends on how far along she is in her pregnancy.
AFP levels are normally high in the early weeks of pregnancy and then decline as the pregnancy progresses.
If the AFP level is too high or too low for the gestational age, it may indicate a problem with the baby’s development.
Choice A is wrong because maternal weight does not affect AFP levels.
Choice B is wrong because fetal heart rate does not affect AFP levels.
Choice D is wrong because the placental function does not affect AFP levels directly, but it may affect the levels of other hormones that are measured along with AFP in a quad screen.
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Related Questions
Correct Answer is B
Explanation
A low level of AFP (<0.5 MoM) in a pregnant woman can indicate that the fetus has a chromosomal abnormality, such as Down syndrome or Edwards syndrome.
This is because these conditions affect the development of the fetal liver, which produces AFP.
Choice A is wrong because neural tube defects, such as spina bifida, are associated with high levels of AFP (>2.5 MoM) in the maternal blood.
This is because AFP can leak from the open spinal canal of the fetus into the amniotic fluid and then into the maternal blood.
Choice C is wrong because maternal weight-related factors do not affect the level of AFP in the maternal blood.
However, they can affect the interpretation of the AFP test results, as the test needs to be adjusted for maternal weight, age, ethnicity, and gestational age.
Choice D is wrong because fetal demise (death) can also cause high levels of AFP in the maternal blood, as the AFP from the dead fetus can leak into the amniotic fluid and then into the maternal blood.
Normal ranges of AFP in pregnant women vary depending on the gestational age and the method of measurement.
Generally, normal levels of AFP are below 10 ng/ml in nonpregnant adults and below 2.5 MoM in pregnant women.
Correct Answer is B
Explanation
Choice A is wrong because it describes a transabdominal CVS procedure, which involves a needle instead of a catheter.
Choice C is wrong because it describes a procedure that is not used for CVS.A needle inserted through the cervix could damage the fetal membranes or cause bleeding.
Choice D is wrong because it describes a procedure that is not possible.A catheter cannot be inserted through the abdomen and uterus into the placenta.
Normal ranges for CVS are not applicable as it is a diagnostic test, not a screening test.
It provides a definitive result of whether the fetus has a chromosomal abnormality or a genetic disorder.CVS is usually done between 10 and 13+6 weeks of pregnancy.
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