A nurse is explaining the purpose of an Alpha-fetoprotein Test (AFP) to a pregnant client.
What is the test primarily used for ?
Screening for neural tube defects.
Assessing placental function.
Determining fetal gender
Diagnosing chromosomal abnormalities
The Correct Answer is A
An alpha-fetoprotein test (AFP) is a blood test that measures the amount of AFP present in blood.
It’s usually part of what’s called a triple screen or quad screen in the second trimester of pregnancy.
The yolk sac, GI tract, and liver of an unborn baby produce AFP.
It then circulates through the fetal and maternal blood.
High levels of AFP in pregnant people can indicate that the baby has a neural tube defect, such as spina bifida or anencephaly.
Choice B is wrong because assessing placental function is not the primary purpose of an AFP test.
However, low levels of AFP can indicate problems with the placenta or the baby’s growth.
Choice C is wrong because determining fetal gender is not the primary purpose of an AFP test.
However, some genetic tests that use a sample of the baby’s DNA from the pregnant person’s blood can reveal the baby’s sex as early as 10 weeks of pregnancy.
Choice D is wrong because diagnosing chromosomal abnormalities is not the primary purpose of an AFP test.
However, an AFP test is usually part of a quad screen that also tests for other markers that can indicate the risk of chromosomal abnormalities, such as Down syndrome.
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Related Questions
Correct Answer is A
Explanation
An NST is a test that measures the fetal heart rate in response to fetal movement.
It is a non-invasive and simple way to assess fetal well-being.
An NST may be recommended to further evaluate fetal well-being if the CST result is equivocal, meaning that occasional but not persistent late decelerations are present.
Choice B. Amniocentesis is wrong because it is an invasive procedure that involves inserting a needle into the uterus to collect amniotic fluid for genetic testing or fetal lung maturity.
It is not used to evaluate fetal well-being in response to contractions.
Choice C. Magnetic resonance imaging (MRI) is wrong because it is an imaging technique that uses magnetic fields to create detailed pictures of the fetus and the placenta.
It is not used to evaluate fetal well-being in response to contractions.
Choice D. Chorionic villus sampling (CVS) is wrong because it is an invasive procedure that involves inserting a catheter or a needle into the placenta to collect chorionic villi for genetic testing.
It is not used to evaluate fetal well-being in response to contractions.
Normal ranges for CST are negative (normal) or positive (abnormal).
Equivocal and unsatisfactory are special categories of test outcomes that require further testing.
Normal ranges for NST are reactive (reassuring) ornon-reactive (non-reassuring).
Correct Answer is B
Explanation
"It is a screening test for spinal defects in the fetus."
The MSAFP test is a blood test that measures the amount of alpha-fetoprotein (AFP) in the mother’s blood.
AFP is a protein produced by the baby during pregnancy.The test helps to assess the baby’s risk of certain birth defects, such as neural tube defects, which are abnormalities in the development of the brain and spine.
A. “It is a diagnostic test for spinal defects in the fetus.” This statement is wrong because the MSAFP test is not a diagnostic test.
It only indicates the probability of having a spinal defect, but it does not confirm or rule out the condition.A diagnostic test, such as an ultrasound or amniocentesis, is needed to make a definitive diagnosis.
C. “It is a diagnostic test for chromosomal abnormalities in the fetus.” This statement is wrong because the MSAFP test is not a diagnostic test for chromosomal abnormalities either.
It only indicates the probability of having a chromosomal abnormality, such as Down syndrome, but it does not confirm or rule out the condition.A diagnostic test, such as a chorionic villus sampling (CVS) or amniocentesis, is needed to make a definitive diagnosis.
D. “It is a screening test for chromosomal abnormalities in the fetus.” This statement is partially correct, but not the best answer.
The MSAFP test alone is not very accurate for screening chromosomal abnormalities.It is usually combined with other blood tests and an ultrasound to form a more reliable screening test called a quad screen or an integrated screen.
The normal range of MSAFP levels varies depending on the gestational age of the baby and the laboratory methods used.Generally, the MSAFP levels increase until about 15 weeks of pregnancy and then decrease until delivery.The average MSAFP level at 15 weeks of pregnancy is about 38 ng/mL.However, different laboratories may have different reference ranges, so it is important to consult your healthcare provider for your specific results and interpretation.
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