A nurse is educating a client who has a respiratory infection and a new prescription for azithromycin (Zithromax).
Which of the following instructions should the nurse include? (Select all that apply).

Take the medication with or without food

Report any signs of jaundice or dark urine

Avoid drinking grapefruit juice while taking this medication

Complete the full course of therapy as prescribed

Store the medication in a cool and dry place.

Answer and Explanation

Correct Answer : B,C,D

Choice A is wrong because azithromycin (Zithromax) should be taken with food to prevent stomach upset.

Choice B is correct because azithromycin can cause liver damage and the client should report any signs of jaundice or dark urine as they may indicate liver problems.

Choice C is correct because azithromycin can interact with grapefruit juice and increase the risk of side effects such as nausea, vomiting, diarrhea, headache and QT interval prolongation.

Choice D is correct because the client should complete the full course of therapy as prescribed to prevent bacterial resistance and recurrence of infection.

Choice E is wrong because azithromycin should be stored in a refrigerator and discarded after 10 days if it is in a liquid form.

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Correct Answer is C

Explanation

Anaphylaxis is a severe allergic reaction that can be life-threatening and requires immediate medical attention.Penicillin is one of the most common causes of anaphylaxis.Symptoms of anaphylaxis include difficulty breathing, swelling of the face, throat, or tongue, hives, itching, low blood pressure, and shock.

Choice A is wrong because hypokalemia (low potassium levels in the blood) is not a common or serious side effect of penicillin therapy.Hypokalemia can cause muscle weakness, cramps, irregular heartbeat, and fatigue.

Choice B is wrong because hyperglycemia (high blood sugar levels) is not a common or serious side effect of penicillin therapy.Hyperglycemia can cause thirst, frequent urination, blurred vision, and headaches.

Choice D is wrong because constipation is not a common or serious side effect of penicillin therapy.Constipation can cause abdominal pain, bloating, and difficulty passing stools.

A. Antibiotic guidelines in critical care reduce the hospital length of stay. B. Inappropriate antibiotic use leads to the emergence of resistance. C. Antibiotic dosing has little effect on antimicrobial resistance. D. An antibiotic stewardship programme leads to an increase in antimicrobial resistance.

Correct Answer is B

Explanation

Inappropriate antibiotic use leads to the emergence of resistance.This is a well-established fact that is supported by the CDC and other organizations.Resistance can occur when antibiotics are used unnecessarily, excessively, or incorrectly, and can lead to infections that are harder to treat and more costly.

Choice A is wrong because antibiotic guidelines in critical care do not necessarily reduce the hospital length of stay.Although some studies have suggested that adherence to pneumonia guidelines may improve outcomes in severe pneumonia, other studies have found no significant effect of antibiotic stewardship on hospital length of stay or mortality in critically ill patients.

Therefore, this statement is not universally true.

Choice C is wrong because antibiotic dosing has a significant effect on antimicrobial resistance.Optimal dosing of antibiotics can help eradicate infections, prevent relapse, and minimize the selection of resistant bacteria.Conversely, suboptimal dosing can lead to treatment failure, prolonged infection, and increased resistance.

Therefore, antibiotic dosing should be carefully adjusted according to the pharmacokinetic and pharmacodynamic properties of the drug and the patient.

Choice D is wrong because an antibiotic stewardship programme leads to a decrease in antimicrobial resistance, not an increase.An antibiotic stewardship programme is a coordinated effort to improve and measure the appropriate use of antibiotics by promoting the selection of the optimal drug regimen, dose, duration, and route of administration.Such programmes have been shown to reduce antibiotic consumption, resistance rates, adverse events, and costs in various settings.

Therefore, this statement is false.

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A nurse is educating a client who has a respiratory infection and a new prescription for azithromycin (Zithromax). Which of the following instructions should the nurse include? (Select all that apply).

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Naxlex Comprehensive Predictor Exams

A nurse is administering penicillin to a client who has streptococcal pharyngitis. The nurse should monitor for which adverse effect of penicillin therapy?

Correct Answer is C

Explanation

Which statement is true regarding antimicrobial stewardship?

Correct Answer is B

Explanation

Which statement is true regarding narrow spectrum antibiotics?

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The nurse identifies which host factor as the most important when choosing an antimicrobial drug?

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A nurse is preparing to administer flucytosine to a client who has a systemic fungal infection. Which of the following assessments should the nurse perform before giving this medication? (Select all that apply.).

A nurse is educating a client who has a respiratory infection and a new prescription for azithromycin (Zithromax).
Which of the following instructions should the nurse include? (Select all that apply).