Which of the following antiviral medications inhibits neuraminidase enzyme?

Cefazolin can cause serious or life-threatening allergic reactions in some patients, especially those with a history of penicillin allergy.The most common allergic reactions to cefazolin are immediate reactions, such as anaphylaxis, urticaria, bronchospasm, and angioedema.These reactions usually occur within one hour of the drug administration and may involve symptoms such as rash, itching, swelling, difficulty breathing, low blood pressure, and shock.Immediate reactions are mediated by immunoglobulin E (IgE) antibodies that bind to the drug and trigger the release of inflammatory mediators from mast cells and basophils.

Choice D is wrong because Stevens-Johnson syndrome is not a typical allergic reaction to cefazolin.

Stevens-Johnson syndrome is a rare and severe skin reaction that can be caused by various drugs, infections, or autoimmune diseases.

It involves blistering and peeling of the skin and mucous membranes, fever, malaise, and eye inflammation.

Stevens-Johnson syndrome is not mediated by IgE antibodies, but by other immune mechanisms that damage the skin cells.

Cefazolin is not known to cause Stevens-Johnson syndrome, although other cephalosporins have been reported to do so in rare cases.

Maraviroc is aCCR5 coreceptor antagonistthat blocks the receptor site the HIV virus needs to interact with in order to enter the cell.It prevents viral fusion with host cell membrane by binding to the CCR5 receptor on CD4+ T cells and macrophages.

Choice B is wrong becauseAbacavir is wrong because it is anucleoside reverse transcriptase inhibitor (NRTI)that inhibits the enzyme reverse transcriptase, which converts viral RNA into DNA.

It does not prevent viral fusion with host cell membrane.

Choice C is wrong becauseDarunavir is wrong because it is aprotease inhibitor (PI)that inhibits the enzyme protease, which cleaves viral proteins into functional units.

It does not prevent viral fusion with host cell membrane.

Choice D is wrong becauseFosamprenavir is wrong because it is also aprotease inhibitor (PI)that inhibits the enzyme protease.

It does not prevent viral fusion with host cell membrane.