Which of the following antiviral medications prevents viral fusion with host cell membrane?

Maraviroc

Abacavir

Darunavir

Fosamprenavir.

Answer and Explanation

The Correct Answer is A

Maraviroc is a CCR5 coreceptor antagonist that blocks the receptor site the HIV virus needs to interact with in order to enter the cell. It prevents viral fusion with host cell membrane by binding to the CCR5 receptor on CD4+ T cells and macrophages.

Choice B is wrong because Abacavir is wrong because it is a nucleoside reverse transcriptase inhibitor (NRTI) that inhibits the enzyme reverse transcriptase, which converts viral RNA into DNA.

It does not prevent viral fusion with host cell membrane.

Choice C is wrong because Darunavir is wrong because it is a protease inhibitor (PI) that inhibits the enzyme protease, which cleaves viral proteins into functional units.

It does not prevent viral fusion with host cell membrane.

Choice D is wrong because Fosamprenavir is wrong because it is also a protease inhibitor (PI) that inhibits the enzyme protease.

It does not prevent viral fusion with host cell membrane.

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Correct Answer is ["A","B","C"]

Explanation

Oxacillin, erythromycin and clindamycin are all antibiotics that are sensitive to Staphylococcus aureus according to the culture and sensitivity report.

This means that they can inhibit or kill the bacteria that are causing the wound infection.These antibiotics belong to different classes of drugs that have different mechanisms of action and spectrum of activity.

Choice D and E are wrong because vancomycin and linezolid are antibiotics that are usually reserved for more resistant strains of Staphylococcus aureus, such as methicillin-resistant Staphylococcus aureus (MRSA) or

A. Antibiotic guidelines in critical care reduce the hospital length of stay. B. Inappropriate antibiotic use leads to the emergence of resistance. C. Antibiotic dosing has little effect on antimicrobial resistance. D. An antibiotic stewardship programme leads to an increase in antimicrobial resistance.

Correct Answer is B

Explanation

Inappropriate antibiotic use leads to the emergence of resistance.This is a well-established fact that is supported by the CDC and other organizations.Resistance can occur when antibiotics are used unnecessarily, excessively, or incorrectly, and can lead to infections that are harder to treat and more costly.

Choice A is wrong because antibiotic guidelines in critical care do not necessarily reduce the hospital length of stay.Although some studies have suggested that adherence to pneumonia guidelines may improve outcomes in severe pneumonia, other studies have found no significant effect of antibiotic stewardship on hospital length of stay or mortality in critically ill patients.

Therefore, this statement is not universally true.

Choice C is wrong because antibiotic dosing has a significant effect on antimicrobial resistance.Optimal dosing of antibiotics can help eradicate infections, prevent relapse, and minimize the selection of resistant bacteria.Conversely, suboptimal dosing can lead to treatment failure, prolonged infection, and increased resistance.

Therefore, antibiotic dosing should be carefully adjusted according to the pharmacokinetic and pharmacodynamic properties of the drug and the patient.

Choice D is wrong because an antibiotic stewardship programme leads to a decrease in antimicrobial resistance, not an increase.An antibiotic stewardship programme is a coordinated effort to improve and measure the appropriate use of antibiotics by promoting the selection of the optimal drug regimen, dose, duration, and route of administration.Such programmes have been shown to reduce antibiotic consumption, resistance rates, adverse events, and costs in various settings.

Therefore, this statement is false.

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Which of the following antiviral medications prevents viral fusion with host cell membrane?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Correct Answer is ["A","B","C"]

Explanation

Which statement is true regarding antimicrobial stewardship?

Correct Answer is B

Explanation

The nurse is caring for a patient receiving vancomycin (Vancocin) for treatment of an infection caused by methicillin-resistant Staphylococcus aureus (MRSA). Which assessment finding would indicate a potentially serious adverse reaction to this drug?

Which of the following antiviral medications prevents viral fusion with host cell membrane?

Which statement is true regarding narrow spectrum antibiotics?

A nurse is reviewing laboratory results for a client who has a fungal infection and is receiving itraconazole therapy. Which of the following findings should alert the nurse to a potential adverse effect of this medication?

A nurse is caring for a client who has a severe infection and is receiving vancomycin (Vancocin). The nurse should monitor the client for which of the following manifestations of ototoxicity?

A nurse is caring for a patient who is receiving gentamicin IV for treatment of endocarditis caused by gram-negative bacteria. Which laboratory value should be monitored closely during gentamicin therapy?

A nurse is preparing to administer vancomycin, a glycopeptide antibiotic, to a client with a severe infection caused by Clostridium difficile. The nurse should select all that apply:

Which antibiotics are classified as concentration-dependent antimicrobials?