A nurse is instructing a colleague on how an antimicrobial produces a therapeutic effect. What should be included in the nurse's teaching?
The first drugs used to treat infections date back to the 17th century.
Fluoroquinolones interfere with the growth and development of the bacteria cell wall.
Selective toxicity determines the appropriate drug dosage needed.
Penicillin interferes with synthesis of the bacteria cell wall.
The Correct Answer is D
A. While historical context is useful, the development of antimicrobials primarily began in the early 20th century, notably with penicillin discovered by Alexander Fleming in 1928.
B. This statement is incorrect; fluoroquinolones primarily inhibit bacterial DNA synthesis rather than directly affecting the cell wall.
C. Selective toxicity is a principle of antimicrobial action but does not directly explain how a specific antimicrobial works therapeutically.
D. Penicillin specifically interferes with the synthesis of the bacterial cell wall, leading to cell lysis and death of the bacteria, which is a fundamental mechanism of action for this antibiotic.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. heart rate is not the primary concern when assessing the interaction between NSAIDs and loop diuretics.
B. blood pressure is correct; the combination of an NSAID and a loop diuretic can lead to fluid retention, potentially elevating blood pressure. Monitoring blood pressure is crucial in this context.
C. cognition is not directly impacted by the combination of these medications.
D. assessment for signs of bleeding is important when taking NSAIDs due to their effect on platelet function, but the more immediate concern is the potential fluid retention affecting blood pressure.
Correct Answer is C
Explanation
A. It has a peak effect of 4-6 hours is incorrect; short-acting insulin typically peaks between 2 to 3 hours after administration.
B. It should be given once daily in the evening is incorrect; short-acting insulin is usually administered before meals, not as a once-daily dose.
C. It starts to take effect within 30 minutes to 1 hour after administration is correct; this timing is critical for managing blood glucose levels during meals.
D. It has a duration of action of 24 hours is incorrect; short-acting insulin usually has a duration of about 3 to 6 hours.
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