A nurse is preparing to administer amoxicillin 500 mg PO. Available is amoxicillin 250 mg tablets.

How many tablets should the nurse administer?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Choice A rationale:
Women experience more problems than men when taking aspirin due to Gastric acidity. Aspirin can cause gastric irritation, and women have been found to have higher gastric acidity than men.
Choice B rationale:
Levels of hepatic enzyme do not specifically cause women to have more problems with aspirin than men. These enzymes are involved in drug metabolism, but their levels do not differ significantly between genders.
Choice C rationale:
Amounts of alcohol dehydrogenase do not cause more problems for women when taking aspirin. This enzyme is involved in alcohol metabolism, not aspirin.
Choice D rationale:
Decreased gastric emptying can increase the risk of gastric irritation from nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin in older adults, but it’s not a gender-specific factor.

Choice A rationale:
Giving the medication as ordered despite the patient’s stated allergy could lead to a severe allergic reaction.
Choice B rationale:
While checking the drug insert for information on reactions to the drug is important, the immediate action should be to withhold the medication.
Choice C rationale:
Withholding the medication and notifying the prescriber of the situation is the safest course of action when a patient states they are allergic to the medication.
Choice D rationale:
Giving the medication and monitoring the patient for adverse effects is not safe if the patient has stated they are allergic to the medication.