A nurse is preparing to administer chlordiazepoxide 50 mg PO every 8 hours to a client. The amount available is chlordiazepoxide 25 mg per capsule. How many capsules should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Choice A Reason: This is incorrect because it adds 10 months and 7 days to the last menstrual period, which is not Nägele's rule.

Choice B Reason: This is incorrect because it adds 9 months and 7 days to the last menstrual period, which is not Nägele's rule.

Choice C Reason: This is correct because it follows Nägele's rule, which is to subtract 3 months and add 7 days to the last menstrual period.

Choice D Reason: This is incorrect because it subtracts 4 months and adds 7 days to the last menstrual period, which is not Nägele's rule.

Choice E Reason: This is incorrect because it subtracts 4 months and adds 17 days to the last menstrual period, which is not Nägele's rule.

Choice A Reason: This is incorrect because sickle-cell anemia is a genetic disorder that affects the shape and function of the red blood cells. It is not related to the AFP level, which is a protein produced by the fetal liver and yolk sac.

Choice B Reason: This is incorrect because cardiac defects are abnormalities in the structure or function of the heart. They are not related to the AFP level, which is a marker of neural tube defects and abdominal wall defects.

Choice C Reason: This is correct because Down syndrome is a chromosomal disorder that results from an extra copy of chromosome 21. It is associated with a decreased AFP level, as well as increased levels of human chorionic gonadotropin (hCG) and unconjugated estriol (uE3).

Choice D Reason: This is incorrect because respiratory disorders are problems that affect the lungs and breathing. They are not related to the AFP level, which reflects the fetal development and integrity.