A nurse is reviewing a client's peak and trough levels of gentamicin. The peak should be 6 to 8 mcg/mL and the trough should be 0.5 to 1 mcg/mL. The client's peak is10 mcg/mL and his trough is 2.3 mcg/mL. Which of the following clinical manifestations should the nurse expect with these findings? (Select all that apply.)

A. A 5 mL syringe can hold up to 5 mL of fluid. It is suitable for administering 2 mL of medication, as it provides enough capacity with some additional space to ensure accurate measurement and prevent overfilling.

B. A 1 mL syringe is too small for administering a 2 mL injection. It would not accommodate the entire volume, and attempting to draw and administer 2 mL with a 1 mL syringe could result in spillage or inaccurate dosing.

C. A 10 mL syringe is larger than necessary for administering a 2 mL injection. While it can hold the required volume and more, it is bulkier and might be less convenient for administering smaller volumes like 2 mL.

D. A 3 mL syringe can also accommodate a 2 mL injection. However, a 5 mL syringe would provide a more appropriate capacity with a bit of extra space, which can be beneficial for accurate measurement and ease of administration.

D. Blurred vision is a known adverse effect of metoclopramide. It can occur due to its effects on the central nervous system, including potential effects on visual processing. Patients should be informed about this potential side effect, and vision should be monitored periodically.

A. Metoclopramide can cause drowsiness or sedation, especially at higher doses or in susceptible individuals. Monitoring for sedation is important to ensure patient safety and adjust dosing as needed.

B. Urinary retention: Although less common, metoclopramide has been associated with urinary retention. Patients should be monitored for signs and symptoms of urinary difficulty or retention, especially if they have pre-existing urinary issues.

C. Hypertension: Metoclopramide can occasionally lead to an increase in blood pressure, particularly in patients who are predisposed to hypertension or have other cardiovascular risk factors. Blood pressure monitoring is important during treatment.