A nurse is reviewing laboratory results for a client who has pericarditis. Which of the following blood test results should the nurse anticipate? (Select All that Apply.)

A. "Vision changes occur when the retina begins to breakdown and collect bits of debris": This statement does not accurately describe the changes that occur in the eye during retinal detachment. Vision changes in retinal detachment primarily occur due to the separation of the retina from its underlying tissue layers, rather than the breakdown and collection of debris within the retina.

B. "Vision changes occur when retinal tissue pulls away from the blood vessels in the eye": Retinal detachment occurs when the retina, which is the light-sensitive layer at the back of the eye, pulls away from its normal position along the inner wall of the eye. This separation disrupts the blood supply to the retina, leading to vision changes. The most common symptom of retinal detachment is the sudden appearance of floaters or flashes of light in the visual field, followed by a shadow or curtain effect as the detachment progresses. Therefore, this statement accurately describes the pathophysiological mechanism underlying vision changes in retinal detachment.

C. "Vision changes occur when the cloudy lens alters the passage of light through the eye": This statement describes changes associated with cataracts, not retinal detachment. Cataracts involve clouding of the lens inside the eye, which can lead to vision changes such as blurriness or decreased visual acuity. However, cataracts are distinct from retinal detachment, which involves the separation of the retina from the inner wall of the eye.

D. "Vision changes occur suddenly due to complete obstruction of aqueous humor outflow": This statement describes the pathophysiology of acute angle-closure glaucoma, not retinal detachment. Acute angle-closure glaucoma is characterized by sudden elevation of intraocular pressure due to complete obstruction of the outflow of aqueous humor, leading to rapid onset of symptoms such as severe eye pain, blurred vision, and halos around lights. Retinal detachment, on the other hand, is characterized by the separation of the retina from its normal position, resulting in distinct vision changes such as floaters, flashes of light, and visual field defects.

A. Respiratory rate of 12/min: A respiratory rate of 12/min is within the normal adult range (12-20 breaths per minute). In the context of increased intracranial pressure (ICP), respiratory rate changes might be noted as part of the Cushing's reflex (which is characterized by bradycardia, hypertension, and abnormal respiratory patterns like Cheyne-Stokes or ataxic breathing), but a rate of 12/min on its own is not indicative of a worsening condition. However, if the patient begins to show signs of irregular or abnormal breathing patterns, this would raise concern.

B. Blood pressure of 108/74 mm Hg: This blood pressure is also within the normal range and does not suggest a worsening of intracranial pressure. In fact, ICP can lead to a rise in blood pressure (due to the body's compensatory mechanisms, known as Cushing's triad), along with bradycardia and abnormal respirations. Thus, a stable blood pressure like 108/74 mm Hg is not concerning in this context.

C. Changes to pupil size and shape: Changes in pupil size, shape, or reactivity are significant indicators of worsening intracranial pressure. Unequal pupils (anisocoria), sluggish or absent response to light, and fixed dilated pupils are signs of brainstem compression or damage, which often occur as ICP increases. This could indicate herniation or severe brain injury, which are worsening conditions.

D. Swelling of the optic nerve: Swelling of the optic nerve, or papilledema, is another important sign of increased intracranial pressure. It occurs due to increased pressure within the skull, which causes congestion and swelling of the optic disc. This finding can be seen on fundoscopy and indicates a worsening condition, as it suggests elevated pressure affecting the brain.

E. Decreasing Glasgow Coma scores: A decreasing Glasgow Coma Scale (GCS) score is a critical indicator of worsening neurologic function in a patient with increased ICP. The GCS is used to assess a patient's level of consciousness, and a decreasing score suggests that the brain's function is deteriorating. This can be caused by worsening edema, brain herniation, or other severe neurological impairments associated with elevated ICP.