A nurse is reviewing the medication record for a client diagnosed with chronic kidney disease (CKD). Which of the following medications should the nurse identify as having the potential to cause nephrotoxicity?
Omeprazole
Ondansetron
Vancomycin
Diphenhydramine
The Correct Answer is C
A. Omeprazole: Not directly nephrotoxic, but long-term use has been associated with interstitial nephritis, although rarely.
B. Ondansetron: Generally safe in renal disease and not known to cause nephrotoxicity.
C. Vancomycin: Known nephrotoxic agent, especially with high trough levels or when used with other nephrotoxins; requires dose adjustment in CKD.
D. Diphenhydramine: Not nephrotoxic; primarily affects the CNS and anticholinergic systems.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. pH 7.49, HCO₃ 24, PaCO₂ 30: Indicates respiratory alkalosis. Not consistent with AKI, which typically causes metabolic acidosis.
B. pH 7.26, HCO₃ 14, PaCO₂ 30: Reflects metabolic acidosis, expected in AKI due to accumulation of acidic waste (low pH, low bicarb), and partial respiratory compensation (low PaCO₂).
C. pH 7.49, HCO₃ 30, PaCO₂ 40: Reflects metabolic alkalosis; not expected in AKI.
D. pH 7.26, HCO₃ 24, PaCO₂ 46: Reflects respiratory acidosis (low pH, elevated CO₂), but bicarb is normal, which does not align with AKI-induced acidosis.
Correct Answer is ["B","C"]
Explanation
A. Assessing the client's support system: Important in overall care, but not a priority in the acute phase.
B. Assessing and removing any rings or jewelry from affected limb: Jewelry can cause constriction due to swelling; removing it prevents further vascular compromise.
C. Assessing the client's circulation distal to the burn site: Circumferential burns can compromise perfusion due to edema or eschar formation. Checking pulses, cap refill, and sensation is essential.
D. Assessing the client's urine output: Important in systemic burns, but not directly related to a localized forearm burn.
E. Assessing the client's respiratory function: Critical in burns involving the face or inhalation injury, but not the forearm.
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