A nurse is teaching a client who has a new prescription for nitroglycerin sublingual tablets for treating angina. Which of the following instructions should the nurse include in the teaching?

A) The client has an increased creatinine level: While an increased creatinine level may indicate renal impairment, it is not specific to a vancomycin infusion reaction. Elevated creatinine levels may occur due to various factors, including underlying kidney disease or dehydration.

B) The client is experiencing hypotension: This is the correct answer. Hypotension, or low blood pressure, can be a manifestation of a vancomycin infusion reaction. Vancomycin infusion reactions may include anaphylaxis or anaphylactoid reactions, which can lead to systemic vasodilation and subsequent hypotension.

C) The client's IV site is red and edematous: Redness ’nd edema at the IV site may indicate phlebitis or infiltration, which are local complications rather than systemic reactions to vancomycin infusion.

D) The client reports ringing in their ears: Ringing in the ears, also known as tinnitus, is a potential side effect of vancomycin, particularly with high doses or prolonged use. However, it is not specific to a vancomycin infusion reaction and may occur independently of the infusion process.

A) Wear gloves when handling the medication: This is the correct action to take when preparing to administer a hazardous IV medication. Wearing gloves helps protect the nurse from direct contact with the medication, reducing the risk of exposure to potentially harmful substances.

B) Administer the medication in a negative pressure room: While some hazardous medications may require administration in a negative pressure room to prevent the spread of airborne contaminants, this is not a standard precaution for administering IV medications. Negative pressure rooms are typically used for airborne infection isolation rather than for medication administration.

C) Administer the medication while wearing protective footwear: While wearing appropriate footwear is important for general safety in healthcare settings, it is not specifically required for administering hazardous IV medications. Protective footwear may be necessary in certain situations, such as when handling biohazardous materials or when there is a risk of spills, but it is not directly related to IV medication administration.

D) Wear an N95 respiratory mask when administering the medication: While respiratory protection may be necessary when handling certain hazardous substances, such as those that produce airborne particles or aerosols, it is not typically required for administering IV medications. N95 masks are primarily used for respiratory protection in situations where there is a risk of inhaling airborne contaminants, such as infectious agents or hazardous chemicals.