A nurse is teaching a client who is beginning highly active antiretroviral therapy (HAART) for HIV which includes zidovudine. The nurse should include teaching regarding which black box warning associated with this medication?
lactic acidosis
Uterine cancer
oral candidiasis
thromboembolic events
The Correct Answer is A
A. Lactic acidosis: Zidovudine has a black box warning for lactic acidosis, a rare but serious complication that can be life-threatening. The nurse should educate the client about symptoms of lactic acidosis, such as muscle pain and weakness.
B. Uterine Cancer: Zidovudine is not associated with uterine cancer.
C. Oral Candidiasis: This is not a black box warning for zidovudine, though oral candidiasis can occur in immunocompromised clients.
D. Thromboembolic Events: This is not a known black box warning for zidovudine.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","D","E"]
Explanation
A. Alopecia: Alopecia is a common side effect of chemotherapy because these medications target rapidly dividing cells, including hair follicles.
B. Bone marrow suppression: Chemotherapy can cause bone marrow suppression, leading to decreased production of blood cells, increasing the risk of anemia, infections, and bleeding.
C. Extrapyramidal symptoms: Extrapyramidal symptoms are associated with antipsychotic medications, not chemotherapy. They include symptoms like tremors, rigidity, and bradykinesia.
D. Bleeding: Due to bone marrow suppression, chemotherapy can decrease platelet counts, increasing the risk of bleeding.
E. Nausea: Nausea and vomiting are common adverse effects of chemotherapy due to the irritation of the gastrointestinal lining and activation of the vomiting center in the brain.
Correct Answer is ["A","C","D","E"]
Explanation
A. Measles: The measles vaccine is a live-attenuated vaccine, which contains a weakened form of the virus and should be avoided in immunocompromised clients due to the risk of infection.
B. Inactivated Polio: The inactivated polio vaccine (IPV) is not a live vaccine, as it uses killed virus, making it safe for immunocompromised clients.
C. Mumps: The mumps vaccine is a live-attenuated vaccine and is part of the MMR (measles, mumps, rubella) vaccine. It should be avoided in clients with weakened immune systems.
D. Varicella: The varicella (chickenpox) vaccine is a live-attenuated vaccine. It should not be given to immunocompromised clients due to the potential risk of severe infection.
E. Rubella: The rubella vaccine is also a live-attenuated vaccine, included in the MMR vaccine, and is contraindicated in immunocompromised individuals.
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