A nurse practitioner is treating a 17-year-old boy who sustained an open tibial fracture in a motor vehicle crash. Which of the following is the most appropriate treatment choice for a grade 1 open fracture?
Aminoglycosides
Cephalosporins
High-dose penicillin
Sulfamethoxazole and trimethoprim
The Correct Answer is B
Choice A reason: Aminoglycosides are primarily used for gram-negative infections and severe open fractures (grade II or III) but are not the first-line choice for a mild, grade 1 open fracture.
Choice B reason: Cephalosporins, particularly first-generation cephalosporins like cefazolin, are the standard prophylactic antibiotics for grade 1 open fractures. They cover common pathogens such as Staphylococcus aureus and reduce the risk of post-traumatic osteomyelitis.
Choice C reason: High-dose penicillin is reserved for fractures complicated by anaerobic infections (e.g., contaminated wounds with soil) and is not routinely indicated for simple grade 1 open fractures.
Choice D reason: Sulfamethoxazole and trimethoprim are not standard prophylaxis for open fractures and are not the first-line treatment due to insufficient coverage of typical pathogens encountered in acute open fractures.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Aminoglycosides are primarily used for gram-negative infections and severe open fractures (grade II or III) but are not the first-line choice for a mild, grade 1 open fracture.
Choice B reason: Cephalosporins, particularly first-generation cephalosporins like cefazolin, are the standard prophylactic antibiotics for grade 1 open fractures. They cover common pathogens such as Staphylococcus aureus and reduce the risk of post-traumatic osteomyelitis.
Choice C reason: High-dose penicillin is reserved for fractures complicated by anaerobic infections (e.g., contaminated wounds with soil) and is not routinely indicated for simple grade 1 open fractures.
Choice D reason: Sulfamethoxazole and trimethoprim are not standard prophylaxis for open fractures and are not the first-line treatment due to insufficient coverage of typical pathogens encountered in acute open fractures.
Correct Answer is C
Explanation
Choice A reason: Bradypnea and bradycardia are not characteristic of fat embolism; fat embolism typically produces compensatory tachycardia and tachypnea.
Choice B reason: Although confusion and shortness of breath can occur, bradycardia and bradypnea are inconsistent with fat embolism syndrome.
Choice C reason: Fat embolism syndrome often presents with tachypnea, tachycardia, restlessness, and a petechial rash, which reflect pulmonary, neurological, and dermatologic involvement, making this the classic presentation.
Choice D reason: Decreased temperature is not a hallmark sign of fat embolism; fever may actually occur in some cases, but tachypnea, tachycardia, restlessness, and petechial rash are the strongest indicators.
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