A patient taking levodopa/carbidopa for Parkinson disease experiences frequent "on-off" episodes (ie, the abrupt loss of effects) Which action by the nurse is best?
Administer the medication when the patient has an empty stomach.
Instruct the patient to avoid high-protein foods.
Have the patient increase the intake of vitamin B6.
Discontinue the drug for 10 days (for a "drug holiday").
The Correct Answer is B
Choice A rationale: Administering the medication with an empty stomach may enhance absorption but is not the best strategy for addressing "on-off" episodes.
Choice B rationale: The correct answer. High-protein foods can interfere with the absorption of levodopa, leading to "on-off" episodes.
Choice C rationale: Vitamin B6 supplementation is not typically used to address "on- off" episodes associated with levodopa/carbidopa.
Choice D rationale: Discontinuing the drug for 10 days (a "drug holiday") is not recommended and may result in a worsening of symptoms.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale: Physical dependence is a state where the body has adapted to the presence of the opioid, and abrupt cessation may lead to withdrawal symptoms. However, the patient's statement indicates tolerance more than physical dependence.
Choice B rationale: The patient is at risk for tolerance, which is the need for an increased dose of a substance to achieve the same effect. This is common in chronic opioid therapy.
Choice C rationale: Abstinence syndrome is another term for withdrawal syndrome, and this is more associated with sudden cessation of opioids.

Correct Answer is C
Explanation
Choice A rationale: Alendronate should be taken in the morning, not at bedtime, and the patient should remain upright for at least 30 minutes afterward to reduce the risk of esophageal irritation and ulceration.
Choice B rationale: Alendronate is often prescribed for longer durations, and the maximum duration is not typically limited to 1 to 2 years. The duration of treatment is individualized based on the patient's risk factors.
Choice C rationale: Alendronate should be taken while sitting upright with plenty of water to ensure proper esophageal transit and minimize the risk of irritation.
Choice D rationale: Alendronate should be taken with plain water, and taking it with coffee or orange juice is not recommended, as it may decrease absorption.
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