A patient is prescribed 500 ml of Normal Saline to be infused over 90 minutes. The drop factor on the tubing is 10 gtt/mL. At what rate should the nurse regulate the IV (gtt/min)? (Round to the nearest whole number)

A. This is a safe medication that is associated with minimal side effects: Carbidopa/levodopa is an effective medication for managing the symptoms of Parkinson's disease, but it is not without side effects. Common side effects include nausea, dizziness, dyskinesia (involuntary movements), and orthostatic hypotension. It is important to be honest with clients about the potential side effects and manage them proactively, rather than describing the medication as "safe with minimal side effects," which could lead to underestimating the risks.

B. Stop the medication if there is increased urination: Increased urination is not a common or typical side effect of carbidopa/levodopa. In fact, the medication is more likely to cause urinary retention or difficulty urinating in some cases. The client should not stop taking the medication without consulting their healthcare provider. Any urinary changes should be reported, but abrupt discontinuation of the medication is not advised without medical supervision.

C. Change position slowly to prevent orthostatic hypotension: One of the common side effects of carbidopa/levodopa therapy is orthostatic hypotension, which occurs when a person experiences a drop in blood pressure upon standing up. This can lead to dizziness or fainting, increasing the risk of falls. The client should be educated to change positions slowly, such as sitting up slowly and standing up gradually from a lying position, to minimize the risk of orthostatic hypotension. This is a critical aspect of safety and should be emphasized as part of the teaching.

D. Double the dose if a dose is missed at the next scheduled time: Doubling the dose of carbidopa/levodopa if a dose is missed can lead to an overdose, which may cause serious side effects, including dyskinesias or other complications. Clients should be instructed to take the missed dose as soon as they remember, unless it is almost time for the next dose. In that case, they should skip the missed dose and continue with their regular dosing schedule. It is important to never double the dose without guidance from the healthcare provider.

A. Decrease in heart rate: While nitroglycerin can sometimes cause reflex tachycardia (an increase in heart rate) as a compensatory mechanism in response to a decrease in blood pressure, its primary effect is on reducing myocardial oxygen demand through vasodilation. Although heart rate may decrease in some situations due to improved perfusion or as a secondary response to pain relief, a decrease in heart rate is not the most reliable or immediate indicator of effectiveness in this context. The relief of chest pain is a more direct measure of the drug's impact.

B. Relief of chest pain: Nitroglycerin works by dilating blood vessels, which reduces myocardial oxygen demand and improves blood flow to the heart, particularly in cases of acute myocardial infarction (MI). The primary therapeutic goal is to relieve chest pain (angina) and reduce the workload of the heart. Monitoring for relief of chest pain is the most direct and important indicator of the medication's effectiveness. If the chest pain decreases or resolves, it suggests that the medication is helping to alleviate the ischemia caused by the MI.

C. Decrease in cardiac dysrhythmias: Nitroglycerin is not primarily used to treat dysrhythmias, although improved perfusion and reduced myocardial oxygen demand may indirectly reduce the occurrence of dysrhythmias in some cases. However, a decrease in dysrhythmias is not a primary goal of nitroglycerin therapy, and the nurse should not primarily monitor for this outcome. Any dysrhythmias should be managed with other specific interventions if needed.

D. Decrease in blood pressure: Nitroglycerin's vasodilatory effect does lead to a reduction in blood pressure, particularly in patients with high blood pressure or in the context of a myocardial infarction. However, excessive hypotension can be dangerous and may lead to inadequate perfusion of vital organs. The nurse must monitor blood pressure closely to avoid hypotension, but a decrease in blood pressure is not the main goal of therapy. The primary objective is to relieve the chest pain associated with the MI. If blood pressure drops too low, it may indicate a need to adjust the dose or discontinue the nitroglycerin.