A patient who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection.
During the patient’s history taking, the nurse finds out that the patient has been self-administering St. John’s Wort, an herbal preparation, on a friend’s advice.
What information is most significant about this finding?
St. John’s Wort can decrease plasma concentrations of cyclosporine.
Consumption of St. John’s Wort can reduce the patient’s sodium intake.
Adding the herb can decrease the need for corticosteroids.
The patient probably used this herb to treat depression.
The Correct Answer is A
Choice A rationale
St. John’s Wort is known to interact with many prescription drugs, including cyclosporine, a medication often given to transplant patients to prevent organ rejection. St. John’s Wort can decrease plasma concentrations of cyclosporine, thus endangering the success of organ transplantations.
Choice B rationale
There is no evidence to suggest that consumption of St. John’s Wort can reduce the patient’s sodium intake.
Choice C rationale
Adding the herb does not decrease the need for corticosteroids. In fact, it can interact with many medications and cause serious complications.
Choice D rationale
While St. John’s Wort is often used to treat depression, in the context of a patient who has undergone a renal transplant, the most significant information is its potential to interact with cyclosporine and endanger the success of the transplant.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["200"]
Explanation
The correct answer is 200 mL/h.
Step 1: The client has been prescribed ciprofloxacin 400 mg intravenously (IV) every 12 hours to be infused over an hour.
Step 2: The IV bag contains ciprofloxacin 400 mg in dextrose 5% in water (D5W) 200 mL12. Step 3: To calculate the infusion rate, the nurse should use the formula: Infusion rate (mL/hr)
= Volume (mL) / Time (hr)3.
Step 4: In this case, the volume is 200 mL and the time is 1 hour. Step 5: Therefore, Infusion rate (mL/hr) = 200 mL ÷ 1 hr.
Step 6: Infusion rate (mL/hr) = 200 mL/hr.
Correct Answer is A
Explanation
Choice A rationale
Risedronate should be taken with a full glass of plain water on an empty stomach, at least 30 minutes before any food, beverage, or other medicines. This is because food and beverages can decrease the absorption of risedronate.
Choice B rationale
Delaying the medication until the patient’s breakfast tray arrives would not be appropriate, as risedronate needs to be taken on an empty stomach.
Choice C rationale
Consulting with a pharmacist about administering the dose one hour post-meal would not be appropriate, as risedronate should be taken on an empty stomach.
Choice D rationale
Assigning an unlicensed assistive personnel to bring the patient a glass of low-fat milk would not be appropriate, as risedronate should be taken with plain water.
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