A client is receiving intravenous vancomycin, and the nurse plans to draw blood for a peak and trough to determine the serum level of the drug.
Which collection times would provide the best determination of these levels?
One hour after completion of the IV dose and one hour before the next administration of the medication.
Two hours after completion of the IV dose and two hours before the next administration of the medication.
Thirty minutes into the administration of the IV dose and 30 minutes before the next administration of the medication.
Immediately after completion of the IV dose and 30 minutes before the next administration of the medication.
The Correct Answer is D
The correct answer is D. Immediately after completion of the IV dose and 30 minutes before the next administration of the medication.
Explanation:
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Peak levels measure the highest concentration of the drug in the bloodstream and should be drawn immediately after the IV infusion is completed.
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Trough levels measure the lowest concentration of the drug and should be drawn 30 minutes before the next scheduled dose. This helps ensure the drug remains within therapeutic levels and prevents toxicity.
Why the other options are incorrect:
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A. One hour after completion of the IV dose and one hour before the next administration – Waiting one hour for the peak level is too long and may lead to an inaccurate measurement.
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B. Two hours after completion of the IV dose and two hours before the next administration – Waiting two hours for both peak and trough levels is too late for effective monitoring.
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C. Thirty minutes into the administration of the IV dose and 30 minutes before the next administration – The sample drawn mid-infusion does not represent peak levels, making this method ineffective.
Key takeaway:
Proper timing of vancomycin peak and trough monitoring ensures therapeutic drug levels while minimizing nephrotoxicity and ototoxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
While it is important to assess for hypoglycemia between meals when a client is receiving insulin lispro, this is not the most important intervention. Hypoglycemia is a potential side effect of all insulins, but the timing of the hypoglycemia is often related to the timing of the insulin dose and meals.
Choice B rationale
Checking blood glucose levels every six hours is a part of diabetes management. However, this is not the most important intervention for a client who is receiving insulin lispro. The timing of blood glucose checks should be individualized based on the client’s needs and the type of insulin they are receiving.
Choice C rationale
Insulin lispro is a rapid-acting insulin that begins to work very quickly. For this reason, it should be given at the same time as meals. This is the most important intervention for a client who is receiving insulin lispro.
Choice D rationale
Keeping an oral liquid or glucose source available is important for all clients with diabetes to treat potential hypoglycemia. However, this is not the most important intervention for a client who is receiving insulin lispro.
Correct Answer is B
Explanation
Choice A rationale
While a thyroid function test could be relevant in some cases, it is not the most pertinent in this situation. The symptoms described by the patient do not suggest a thyroid issue.
Choice B rationale
The symptoms described by the patient, such as fatigue, nausea, dark urine, and yellowing of the skin and sclera, are indicative of liver dysfunction. Albendazole is primarily metabolized in the liver, and its use can cause liver damage in some cases. Therefore, a liver function test would be the most appropriate laboratory result to review.
Choice C rationale
While a renal function panel could be relevant in some cases, it is not the most pertinent in this situation. The symptoms described by the patient do not suggest a kidney issue.
Choice D rationale
A basic metabolic panel could provide useful information about various aspects of the patient’s health, but it is not the most relevant test given the patient’s symptoms and medication.
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