A patient will be starting therapy with a corticosteroid. The nurse reviews the prescriber's orders and notes that an interaction may occur if the corticosteroid is taken with which of these drug classes?
Antibiotics
Nonsteroidal anti-inflammatory drugs
Opioid analgesics
Antidepressants
The Correct Answer is B
Choice A reason: Antibiotics are not likely to interact with corticosteroids, unless they are aminoglycosides, which can increase the risk of hypokalemia. However, most antibiotics do not affect the metabolism or efficacy of corticosteroids.
Choice B reason: Nonsteroidal anti-inflammatory drugs (NSAIDs) can interact with corticosteroids, as they both have anti-inflammatory and immunosuppressive effects. This can increase the risk of gastrointestinal bleeding, ulceration, and perforation. Therefore, the nurse should monitor the patient for signs of bleeding and advise the patient to avoid taking NSAIDs with corticosteroids.
Choice C reason: Opioid analgesics are not likely to interact with corticosteroids, unless they are codeine, which can decrease the clearance of corticosteroids. However, most opioid analgesics do not affect the metabolism or efficacy of corticosteroids.
Choice D reason: Antidepressants are not likely to interact with corticosteroids, unless they are monoamine oxidase inhibitors (MAOIs), which can increase the risk of hypertension and hypertensive crisis. However, most antidepressants do not affect the metabolism or efficacy of corticosteroids.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: This is incorrect because the patient may not see a response from the medication for at least six months. The patient should continue taking the medication as prescribed and follow up with the provider regularly.
Choice B reason: This is correct because finasteride can cause birth defects in male fetuses if it is absorbed through the skin or ingested by pregnant women. The patient should wear gloves when handling the tablets and avoid contact with crushed or broken tablets.
Choice C reason: This is incorrect because PSA levels will decrease while taking this medication. PSA stands for prostate-specific antigen, which is a marker for prostate cancer. The patient should inform the provider that they are taking finasteride before having a PSA test, as it may affect the results.
Choice D reason: This is incorrect because grapefruit juice does not interact with finasteride. However, the patient should avoid alcohol and other medications that may affect the liver while taking finasteride.
Correct Answer is C
Explanation
Choice A reason: Respiratory rate and heart rate are not specific indicators of oxygen saturation. They can be affected by many other factors, such as pain, anxiety, or dehydration.
Choice B reason: Blood pressure and temperature are not directly related to oxygen saturation. They can be influenced by other conditions, such as infection, inflammation, or shock.
Choice C reason: Lung sounds and chest expansion are relevant parameters to monitor for a client with low oxygen saturation. They can indicate the presence of respiratory problems, such as pneumonia, asthma, or atelectasis, that can impair gas exchange and oxygen delivery.
Choice D reason: Hemoglobin and hematocrit are measures of red blood cell count and volume. They can affect the oxygen-carrying capacity of the blood, but they are not directly affected by oxygen saturation. They can be altered by other factors, such as bleeding, dehydration, or anemia.
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