A young client desires to know her risk of developing breast carcinoma. She has a positive family history of breast carcinoma. The nurse would suggest that she should undergo which diagnostic test?
DNA ploidy status
digital mammography
BRCA-1 genetic marker
fine-needle biopsy
The Correct Answer is C
A. DNA ploidy status: This test analyzes the number and structure of chromosomes within tumor cells to determine malignancy aggressiveness. It is used after cancer is diagnosed, not for assessing hereditary risk in an asymptomatic person.
B. Digital mammography: Mammography is a screening tool for detecting existing breast abnormalities or early cancer, not a genetic risk assessment. It is recommended for routine screening, typically starting at age 40 or earlier if the woman is at high risk.
C. BRCA-1 genetic marker: Testing for BRCA-1 (and BRCA-2) mutations identifies women with a hereditary predisposition to breast and ovarian cancer. A positive result indicates a significantly higher lifetime risk and guides preventive and surveillance strategies.
D. Fine-needle biopsy: This diagnostic procedure is used to evaluate an existing breast lump or suspicious lesion for malignancy. It does not identify genetic or hereditary cancer risk in asymptomatic individuals.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Genetic testing for BRCA genes: BRCA testing is indicated for women with a strong family history or known genetic risk of breast cancer, not as the initial diagnostic step for a newly detected breast lump. It helps assess genetic susceptibility but does not diagnose the current mass.
B. Fine-needle aspiration: Fine-needle aspiration is used later to obtain tissue or fluid for cytologic analysis once imaging confirms a suspicious lesion. It is not the first step before confirming the lump’s characteristics through imaging.
C. Hormone receptor status: Hormone receptor testing is performed only after a confirmed diagnosis of breast cancer from biopsy results. It guides treatment decisions but is not part of the initial workup.
D. Mammogram: A diagnostic mammogram is the appropriate next step to evaluate the characteristics of the lump, determine its location, and identify any additional suspicious areas. Imaging helps differentiate benign from malignant features before proceeding to biopsy or further tests.
Correct Answer is D
Explanation
A. "An oophorectomy will prevent you from having breast cancer in the future.": While removing the ovaries reduces estrogen production and may slightly lower the risk of hormone-dependent cancers, it does not eliminate the possibility of developing breast cancer.
B. "You will need to continue using a contraceptive if you do not desire pregnancy.": After bilateral oophorectomy, both ovaries are removed, halting ovulation permanently and making pregnancy impossible. Therefore, contraception is no longer necessary.
C. "You will need to have your hormone level tested monthly for 6 months following surgery.": Routine monthly hormone testing is not required after oophorectomy. Hormonal changes are expected, and management is typically guided by symptoms rather than frequent laboratory monitoring.
D. "This procedure will greatly reduce your estrogen and progesterone levels.": The ovaries are the primary source of estrogen and progesterone production. Their removal leads to a sudden decline in these hormones, resulting in surgical menopause and symptoms such as hot flashes, vaginal dryness, and mood changes.
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