After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?
To suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
To suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
To inhibit production of thyroid hormone in the thyroid gland.
To destroy part of the thyroid gland.
The Correct Answer is C
Propylthiouracil (PTU) is an antithyroid drug that blocks the synthesis of thyroid hormones by interfering with the oxidation of iodine and the coupling of iodotyrosines.
This reduces the levels of triiodothyronine (T) and thyroxine (T) in the blood and relieves the symptoms of hyperthyroidism.
Choice A is wrong because PTU does not destroy any part of the thyroid gland.
It only inhibits the production of thyroid hormones within the gland.
Choice B is wrong because PTU does not suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
TSH is a hormone that stimulates the thyroid gland to produce thyroid hormones.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Choice D is wrong because PTU does not suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
TRH is a hormone that stimulates the pituitary gland to secrete TSH.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Normal ranges for T are 80 to 220 ng/dL, for T are 4.5 to 11.2 mcg/dL, and for TSH are 0.4 to 4.0 mIU/L.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Prednisone is a glucocorticoid that suppresses the production of natural cortisol by the adrenal glands. Taking prednisone on alternate days allows the adrenal glands to recover and produce some cortisol on the days without prednisone.
Choice B is wrong because prednisone does not eliminate adverse side effects, but may cause some such as weight gain, fluid retention, increased blood pressure, increased blood glucose, and increased risk of infection.
Choice C is wrong because there is no evidence of steroid tolerance, which means that higher doses are needed to achieve the same effect.
Choice D is wrong because prednisone does not prolong therapeutic effects, but may decrease them over time due to feedback inhibition of cortisol secretion.
Normal ranges for cortisol are 6 to 23 mcg/dL in the morning and 2 to 11 mcg/dL in the afternoon.
Correct Answer is C
Explanation
The nurse should advise the client to avoid aluminum salts because they can increase the risk of aluminum toxicity when taken with sucralfate. Sucralfate forms a protective coating over the ulcer and binds to aluminum in the stomach.
Choice A is wrong because Milk of Magnesia is a magnesium-based antacid that can cause diarrhea, but does not interact with sucralfate.
Choice B is wrong because Calcium carbonate is a calcium-based antacid that can cause constipation, but does not interact with sucralfate.
Choice D is wrong because Proton pump inhibitors are drugs that reduce the production of stomach acid and can help heal ulcers.
They do not interact with sucralfate.
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