After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?

To suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).

To suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).

To inhibit production of thyroid hormone in the thyroid gland.

To destroy part of the thyroid gland.

Answer and Explanation

The Correct Answer is C

Propylthiouracil (PTU) is an antithyroid drug that blocks the synthesis of thyroid hormones by interfering with the oxidation of iodine and the coupling of iodotyrosines.

Thyroid and Antithyroid Drugs - Katzung & Trevor's Pharmacology Examination and Board Review, 9th Edition

This reduces the levels of triiodothyronine (T) and thyroxine (T) in the blood and relieves the symptoms of hyperthyroidism.

Choice A is wrong because PTU does not destroy any part of the thyroid gland.

It only inhibits the production of thyroid hormones within the gland.

Choice B is wrong because PTU does not suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).

TSH is a hormone that stimulates the thyroid gland to produce thyroid hormones.

PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.

Choice D is wrong because PTU does not suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).

TRH is a hormone that stimulates the pituitary gland to secrete TSH.

PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.

Normal ranges for T are 80 to 220 ng/dL, for T are 4.5 to 11.2 mcg/dL, and for TSH are 0.4 to 4.0 mIU/L.

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Correct Answer is B

Explanation

The client should avoid taking aspirin while taking corticosteroids because of the potential drug-drug interaction between them. This interaction may cause a reduction in the blood levels of aspirin and decrease its effectiveness. It may also increase the risk of gastrointestinal side effects such as inflammation, bleeding, ulceration, and perforation.

Choice A is wrong because dimenhydrinate is an antihistamine that is used to prevent and treat nausea, vomiting, and dizziness.

It does not have a significant interaction with corticosteroids.

Choice C is wrong because ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, inflammation, and fever.

It has a similar interaction with corticosteroids as aspirin, but it is less potent and less likely to cause bleeding.

Choice D is wrong because famotidine is a histamine-2 receptor antagonist that is used to treat and prevent ulcers, gastroesophageal reflux disease (GERD), and other conditions that cause excess stomach acid.

It does not have a significant interaction with corticosteroids.

A. A client who has been diagnosed with gestational diabetes. B. A client with type 2 diabetes, controlled with oral antidiabetic agents, who has a systemic infection. C. A client whose type 2 diabetes is controlled by diet and exercise. D. A client who has been living with type 1 diabetes for 20 years.

Correct Answer is C

Explanation

The nurse should question the administration of human insulin to this client because they do not need exogenous insulin to maintain normal blood glucose levels. Human insulin is indicated for clients who have type 1 diabetes or type 2 diabetes that cannot be controlled by oral antidiabetic agents, diet, or exercise.

Choice A is wrong because a client who has been diagnosed with gestational diabetes may need human insulin to control their blood glucose levels during pregnancy, as oral antidiabetic agents are contraindicated.

Choice B is wrong because a client with type 2 diabetes, controlled with oral antidiabetic agents, who has a systemic infection may need human insulin to manage their blood glucose levels during periods of stress, as infection can increase blood glucose levels and impair the action of oral antidiabetic agents.

Choice D is wrong because a client who has been living with type 1 diabetes for 20 years needs human insulin to replace the endogenous insulin that their pancreas cannot produce.

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After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is providing client education to a client who has had corticosteroids prescribed. What drug should the nurse teach the client to avoid while taking the corticosteroids?

Correct Answer is B

Explanation

With what client should the nurse question the administration of human insulin?

Correct Answer is C

Explanation

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