Alcohol acts as a diuretic because it
is not reabsorbed by the tubule cells
increases the rate of glomerular filtration
increases secretion of ADH
inhibits the release of ADH
The Correct Answer is D
A. is not reabsorbed by the tubule cells: While some substances like mannitol act as osmotic diuretics because they remain in the tubule lumen, alcohol follows a different physiological pathway. Alcohol is a lipid-soluble molecule that can diffuse across membranes rather than relying on tubular transport inhibition. Its diuretic effect is neuroendocrine in origin rather than purely osmotic.
B. increases the rate of glomerular filtration: Although alcohol can cause minor changes in systemic blood pressure, it does not significantly increase the glomerular filtration rate as its primary mode of action. A slight increase in flow would not account for the profound volume of dilute urine produced. The primary diuretic effect occurs later in the distal segments of the nephron.
C. increases secretion of ADH: Increased secretion of antidiuretic hormone would result in the insertion of aquaporins and the retention of water, leading to concentrated urine. This is the opposite of the clinical effect observed with alcohol consumption. Stimulating ADH would prevent diuresis rather than promote it, leading to fluid volume expansion.
D. inhibits the release of ADH: Ethanol directly suppresses the hypothalamic-hypophyseal tract, reducing the secretion of antidiuretic hormone from the posterior pituitary. Without ADH, the collecting ducts remain impermeable to water, preventing reabsorption and resulting in the excretion of large volumes of dilute urine. This inhibition is the primary cause of alcohol-induced dehydration.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. osmosis. Water moves passively across the renal tubular epithelium following osmotic gradients established by the active transport of solutes like sodium. This process, often referred to as obligatory water reabsorption in the proximal tubule, allows water to diffuse through aquaporins. It does not require direct ATP consumption for the water molecules themselves.
B. filtration. Filtration is the process that occurs exclusively in the renal corpuscle where blood is processed into filtrate. Once the fluid enters the renal tubules, the movement of substances back into the blood is classified as reabsorption. Filtration is driven by hydrostatic pressure, whereas tubular water movement is driven by osmotic concentration differences.
C. active transport. There are no known biological pumps that directly use ATP to move water molecules against a concentration gradient. Biological systems move water by actively transporting solutes and allowing water to follow passively. All water movement in the kidney is a response to osmotic or hydrostatic forces rather than direct active pumping.
D. cotransport with sodium ions. While many solutes like glucose and amino acids use secondary active transport (cotransport) with sodium, water moves through separate channel proteins called aquaporins. Sodium reabsorption creates the osmotic drive, but the water molecules do not bind to the carrier proteins alongside sodium. Water movement is the result of the sodium transport, not a shared transport mechanism.
Correct Answer is A
Explanation
A. 4; 1: During spermatogenesis, a single primary spermatocyte undergoes two meiotic divisions to produce four functional, haploid spermatozoa. In contrast, oogenesis involves asymmetrical cytokinesis, where one primary oocyte yields only one functional secondary oocyte and three non-functional polar bodies. This allows the single ovum to retain the cytoplasm necessary for early embryonic life.
B. 4; 2: Oogenesis does not result in two functional ova under normal physiological conditions. While two polar bodies may be visible at different stages, only one cell matures into the gamete capable of being fertilized. Producing two functional eggs would be the result of a double ovulation event rather than the standard meiotic process.
C. 2:4: This ratio is the reverse of biological reality. Males produce significantly more gametes per meiotic event than females to ensure a higher probability of fertilization. Females prioritize the quality and nutrient content of a single cell over the quantity of gametes produced. This ensures the zygote has an adequate supply of organelles.
D. 4; 4: If oogenesis produced four functional ova, human multiple births would be the standard rather than the exception. The energy cost of producing four nutrient-rich eggs is too high for the female reproductive strategy. Asymmetrical division is a specific evolutionary adaptation to ensure the survival of a single fertilized zygote.
E. 1; 4: This choice suggests males produce fewer gametes than females per meiotic cycle, which is incorrect. A single spermatogonium eventually leads to the production of four spermatids through the process of meiosis. Oogenesis is the pathway that results in a single functional gamete due to the formation of polar bodies.
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