Alcohol acts as a diuretic because it
is not reabsorbed by the tubule cells
increases the rate of glomerular filtration
increases secretion of ADH
inhibits the release of ADH
The Correct Answer is D
A. is not reabsorbed by the tubule cells: While some substances like mannitol act as osmotic diuretics because they remain in the tubule lumen, alcohol follows a different physiological pathway. Alcohol is a lipid-soluble molecule that can diffuse across membranes rather than relying on tubular transport inhibition. Its diuretic effect is neuroendocrine in origin rather than purely osmotic.
B. increases the rate of glomerular filtration: Although alcohol can cause minor changes in systemic blood pressure, it does not significantly increase the glomerular filtration rate as its primary mode of action. A slight increase in flow would not account for the profound volume of dilute urine produced. The primary diuretic effect occurs later in the distal segments of the nephron.
C. increases secretion of ADH: Increased secretion of antidiuretic hormone would result in the insertion of aquaporins and the retention of water, leading to concentrated urine. This is the opposite of the clinical effect observed with alcohol consumption. Stimulating ADH would prevent diuresis rather than promote it, leading to fluid volume expansion.
D. inhibits the release of ADH: Ethanol directly suppresses the hypothalamic-hypophyseal tract, reducing the secretion of antidiuretic hormone from the posterior pituitary. Without ADH, the collecting ducts remain impermeable to water, preventing reabsorption and resulting in the excretion of large volumes of dilute urine. This inhibition is the primary cause of alcohol-induced dehydration.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. The sister chromatids are separated from each other: During the first meiotic division, the goal is to reduce the chromosome number by separating homologous pairs. The separation of sister chromatids is the defining event of meiosis 2 or mitosis, not meiosis 1. In meiosis 1, sister chromatids remain attached at the centromere as they move toward the poles.
B. Portions of maternal chromosomes crossover with equivalent portions of paternal chromosomes: Synapsis and crossing over occur during prophase 1, where non-sister chromatids of homologous chromosomes exchange genetic material. This process increases genetic diversity by creating new combinations of alleles. It is a hallmark event that occurs exclusively during the first division of meiosis.
C. The homologous chromosomes are separated from each other: Anaphase 1 focuses on pulling apart the pairs of chromosomes inherited from each parent. This ensures that each daughter cell receives only one member of each pair, though each member still consists of two chromatids. This separation is the physical basis for the law of segregation in genetics.
D. A single diploid (2n) nucleus has become two haploid (n) nuclei: Meiosis 1 is referred to as a reductional division because it halves the chromosome count. The starting cell begins with 46 chromosomes in humans, and the resulting daughter cells each contain 23 chromosomes. This transition from diploid to haploid occurs specifically during the cytokinesis following telophase 1.
Correct Answer is A
Explanation
A. transitional ET: This specialized epithelium is unique to the urinary tract and allows for significant distension. The cells can shift from a rounded, cuboidal shape to a flattened appearance as the bladder fills. This structural flexibility prevents tissue damage during volume fluctuations.
B. simple squamous ET: This single layer of flat cells is adapted for rapid filtration and diffusion rather than stretching. It is found in the parietal layer of the glomerular capsule and the thin limb of the loop of Henle. It lacks the durability required for a storage organ.
C. simple cuboidal ET: These cells are primarily involved in secretion and absorption within the renal tubules. They often possess microvilli to increase surface area for transport. This tissue type does not provide the stratified protection or distensibility needed for the bladder wall.
D. stratified squamous ET: This tissue provides protection against mechanical abrasion in areas like the skin or esophagus. While it is multi-layered, it does not have the ability to stretch and recoil like transitional cells. It is generally found in the distal portion of the urethra.
E. pseudostratified columnar ET epithelium: This tissue type is characteristic of the respiratory tract where it often possesses cilia and goblet cells. It is designed for moving mucus and debris rather than containing liquid under pressure. It does not occur in the lining of the urinary bladder.
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