______ are secreted by cells infected with viruses, alerting neighboring cells and protecting them from becoming infected.
Complement system globulins
Interferons
Granzymes
Pyrogens
Perforins
The Correct Answer is B
A. Complement system globulins: These are a group of plasma proteins synthesized primarily by the liver that circulate in an inactive state. They are activated by a cascade mechanism to enhance phagocytosis, inflammation, and cytolysis of pathogens. They are not specifically secreted by virus-infected cells to alert neighboring cells.
B. Interferons: When a cell is compromised by a viral pathogen, it synthesizes and releases these signaling proteins as a paracrine defense. Interferons bind to receptors on adjacent healthy cells, triggering the production of antiviral proteins that inhibit viral replication. They act as a critical early warning system in the innate immune response.
C. Granzymes: These are proteolytic enzymes released by natural killer cells and cytotoxic T lymphocytes via exocytosis. They enter a target cell through pores to induce programmed cell death or apoptosis. Their function is the direct destruction of infected or neoplastic cells rather than the signaling of neighbors.
D. Pyrogens: These substances, such as interleukin 1, act on the hypothalamus to elevate the body's temperature set point, resulting in fever. While they are part of the systemic inflammatory response, they do not provide localized cellular protection against viral entry. They modulate systemic thermoregulation rather than cellular viral resistance.
E. Perforins: These are pore-forming proteins secreted by effector lymphocytes to compromise the structural integrity of a target cell's plasma membrane. By creating holes in the membrane, they allow granzymes to enter and facilitate rapid cytolysis. They are tools of direct cellular execution rather than prophylactic intercellular signaling.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Digestion: This physiological process involves both mechanical mastication and chemical hydrolysis to convert complex food into absorbable molecules. It begins in the oral cavity and continues through the stomach and small intestine. It is the specific term for the multi-modal breakdown of nutritional matter.
B. Ingestion: This term refers specifically to the act of taking food or liquid into the body via the oral cavity. It is the entry phase of the nutritional process rather than the breakdown mechanism itself. Digestion follows ingestion but represents a distinct set of biochemical and physical actions.
C. Compaction: This process occurs primarily in the large intestine where water is absorbed from indigestible residue. It converts liquid chyme into consolidated feces for eventual excretion. It involves the dehydration of waste products rather than the constructive breakdown of food for nutrient extraction.
D. Absorption: This stage involves the movement of digested nutrients from the lumen of the gastrointestinal tract into the blood or lymph. It occurs after the mechanical and chemical breakdown of food is largely complete. It describes the uptake of molecules, not the process of breaking them down.
E. Extraction: In a biological context, this word is often used generally for the removal of specific substances from a mixture. It is not the standard clinical term used to describe the integrated digestive functions of the alimentary canal. It lacks the specificity required to describe human gastrointestinal physiology.
Correct Answer is C
Explanation
A. Trachea: The trachea, or windpipe, marks the beginning of the lower respiratory tract. It is located inferior to the larynx and serves as the conduit to the primary bronchi. Including the trachea within the upper respiratory tract contradicts standard clinical and anatomical classification systems.
B. Pharynx: The pharynx is a muscular funnel that connects the nasal cavity to the larynx. While it is a critical component of the upper respiratory system, the tract extends further down to include the vocal apparatus. Classification ends at the transition point between the larynx and the trachea.
C. Larynx: The upper respiratory tract encompasses the nasal cavity, pharynx, and the larynx. The larynx serves as the anatomical boundary before the air enters the tracheobronchial tree. Structures located from the trachea downwards are categorized as the lower respiratory tract in medical anatomy.
D. Alveoli: Alveoli are the microscopic sites of gas exchange located at the terminal ends of the bronchial tree. They are the deepest structures within the lower respiratory tract. Defining them as part of the upper respiratory system ignores the vast anatomical distance from the nose.
E. Lungs: The lungs are the primary organs of the lower respiratory system, containing the bronchi, bronchioles, and alveolar sacs. They are situated within the thoracic cavity, protected by the rib cage. The upper respiratory tract is limited to the structures superior to the thoracic inlet.
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