Based on the classification system of pharmacodynamics, which category statements are accurate? (Select all that apply.)

A. The patient is experiencing withdrawal symptoms: Withdrawal symptoms occur when a patient stops taking a medication suddenly after long-term use. However, the scenario does not describe withdrawal symptoms, but rather a loss of effectiveness of the medication.

B. The patient is habituated to the medication: Habituation refers to psychological dependence on a medication, which does not directly explain why the medication is no longer effective.

C. The patient is addicted to the medication: Addiction involves compulsive use of a drug despite harmful consequences and does not explain the loss of effectiveness described.

D. The patient is experiencing tolerance: Tolerance occurs when the body becomes accustomed to a drug, and higher doses are needed to achieve the same effect. The scenario describes tolerance, where the patient feels the medication no longer works.

A. Notify the charge nurse that patients may have received inappropriate medication dosages.
Jumping to conclusions about inappropriate dosages without first investigating the rationale for the dosing is premature and could cause unnecessary alarm.

B. Evaluate the laboratory values of each patient to determine liver and kidney function as a possible reason for decreased dosages. Lower dosages are often prescribed for older adults due to decreased liver and kidney function, which can affect drug metabolism and excretion. Evaluating lab values ensures that these dosages are appropriate and safe.

C. Do not worry about the discrepancy because this is not the nurse's unit.
Ignoring the discrepancy is not appropriate, as it’s important for all nurses to advocate for patient safety, regardless of the unit.

D. Call the nursing supervisor to investigate the nurse's concerns.
The nursing supervisor may need to be involved, but the first step is to review the relevant clinical data (lab values) to assess the situation.