The LPN/LVN is aware that the bioavailability of a drug is based on multiple factors. Which factor(s) would be included? Select all that apply.
molecular weight
fat or liquid solubility
depth of breathing
development of a fever
presence of food
Correct Answer : A,B,E
A. Molecular weight: Drugs with lower molecular weight tend to have higher bioavailability because they can more easily pass through biological membranes.
B. Fat or liquid solubility: Drugs that are fat-soluble can cross cell membranes more easily, affecting their bioavailability. Water-soluble drugs may require transport mechanisms, which can limit absorption.
C. Depth of breathing: The depth of breathing primarily affects the absorption of inhaled drugs, not the general bioavailability of orally or intravenously administered medications.
D. Development of a fever: While fever can affect drug metabolism, it doesn’t directly influence the bioavailability of a drug.
E. Presence of food: Food in the stomach can either enhance or inhibit drug absorption, depending on the drug’s characteristics. This directly impacts bioavailability.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B"]
Explanation
A. Intramuscular: Intramuscular (IM) injections are absorbed faster than oral medications due to the richer blood supply in muscles compared to subcutaneous tissues.
B. Intravenous: Intravenous (IV) administration provides immediate systemic absorption as the medication is delivered directly into the bloodstream.
C. Topically: Topical medications are applied to the skin and generally have a slower absorption rate compared to systemic routes.
D. Transdermal: Transdermal patches provide a steady, controlled release of medication through the skin, but absorption is slower compared to IM and IV routes.
E. Oral pills: Oral medications are absorbed through the gastrointestinal tract, which is slower compared to IM and IV routes.
Correct Answer is A
Explanation
A. Ask the patient if they have used any holistic medications previously. This approach respects the patient's preferences and opens a dialogue about their health beliefs and practices. Understanding the patient's use of holistic remedies allows the nurse to provide more personalized care and address potential interactions with prescribed medications.
B. Notify the health-care provider that the patient has refused the medication.
This step might be necessary eventually, but first, the nurse should explore the patient's concerns and preferences to see if a solution can be reached.
C. Tell the patient to talk to the health-care provider when they make rounds.
This response delays addressing the patient's concerns and misses an opportunity for the nurse to engage with the patient directly.
D. Tell the patient that the health-care provider would not order the medication unless it was necessary.
This response dismisses the patient's concerns and does not consider their cultural beliefs, which may lead to decreased trust and cooperation.
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