The LPN/LVN is aware that the bioavailability of a drug is based on multiple factors. Which factor(s) would be included? Select all that apply.
molecular weight
fat or liquid solubility
depth of breathing
development of a fever
presence of food
Correct Answer : A,B,E
A. Molecular weight: Drugs with lower molecular weight tend to have higher bioavailability because they can more easily pass through biological membranes.
B. Fat or liquid solubility: Drugs that are fat-soluble can cross cell membranes more easily, affecting their bioavailability. Water-soluble drugs may require transport mechanisms, which can limit absorption.
C. Depth of breathing: The depth of breathing primarily affects the absorption of inhaled drugs, not the general bioavailability of orally or intravenously administered medications.
D. Development of a fever: While fever can affect drug metabolism, it doesn’t directly influence the bioavailability of a drug.
E. Presence of food: Food in the stomach can either enhance or inhibit drug absorption, depending on the drug’s characteristics. This directly impacts bioavailability.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D"]
Explanation
A. Replacement medications provide needed physiological components: Replacement therapy provides substances that the body is deficient in, such as insulin for diabetes.
B. Destructive medications are always curative: Destructive medications, such as chemotherapeutic agents, may destroy pathological cells but are not always curative.
C. Palliative therapy provides pain relief: Palliative therapy aims to relieve symptoms and improve quality of life rather than cure.
D. Diagnostic drugs help to identify pathological processes: Diagnostic drugs are used in tests and procedures to help identify and diagnose diseases.
E. Prophylactic medications are curative: Prophylactic medications are used to prevent diseases, not cure them.
Correct Answer is A
Explanation
A. Barium sulfate is used as a contrast agent in radiographic diagnostic testing, particularly for imaging the gastrointestinal tract.
B. Penicillin (PCN) is an antibiotic used to treat infections, not for diagnostic purposes.
C. Estrogen is a hormone used in hormone replacement therapy and other treatments, not for diagnostic testing.
D. Naloxone is used to reverse opioid overdose, not for diagnostic testing.
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