In bipolar disorder, it is theorized that initial episodes are likely triggered by major life events that cause the brain to become overly sensitive to electrical stimulation. Successive episodes grow increasingly more autonomous due to neuronal misfiring. Which term represents this concept?
GABA deregulation
Kindling
Genetic loading
Voltage-gated channel abnormalities
The Correct Answer is B
Choice A reason: GABA deregulation refers to disruptions in inhibitory neurotransmission, which may contribute to bipolar symptoms but does not specifically explain the progressive sensitization seen with repeated episodes.
Choice B reason: Kindling describes the process by which repeated subthreshold stimulation of neurons eventually leads to spontaneous, autonomous activity. In bipolar disorder, initial episodes are triggered by stressors, but later episodes may occur with decreasing external provocation, reflecting the kindling phenomenon.
Choice C reason: Genetic loading refers to inherited susceptibility to bipolar disorder but does not account for the progressive, self-propagating nature of episodes.
Choice D reason: Voltage-gated channel abnormalities may play a role in neuronal excitability but do not specifically describe the phenomenon of progressive autonomy in episode recurrence seen in bipolar disorder.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Rapid cycling is associated with a poorer response to lithium, often requiring alternative or adjunctive therapies.
Choice B reason: Clear euthymic intervals between episodes are associated with classic bipolar disorder, which predicts a favorable response to lithium treatment.
Choice C reason: Psychotic symptoms do not reliably predict lithium response; these patients may require additional antipsychotic therapy.
Choice D reason: Mixed episodes often respond less predictably to lithium alone and may need combination therapy.
Correct Answer is A
Explanation
Choice A reason: Dissociative identity disorder is characterized by the presence of two or more distinct identities or personality states and amnesia for daily events, which aligns with the patient’s symptoms.
Choice B reason: Adjustment disorder involves emotional or behavioral symptoms in response to a stressor but does not include dissociation or multiple identities.
Choice C reason: Schizotypal personality disorder involves eccentric behavior, perceptual distortions, and odd beliefs but does not include distinct identities or memory gaps.
Choice D reason: Malingering is intentional production of false symptoms for external gain, whereas this patient demonstrates involuntary dissociative experiences.
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