It is determined that a client's blood Rh is negative and her partner's is positive. To help prevent Rh isoimmunization, the nurse would expect to administer Rho(D) immune globulin at which time?
24 hours before delivery and 24 hours after delivery
In the first trimester and within 2 hours of delivery
At 28 weeks gestation and again within 72 hours after delivery
At 32 weeks gestation and immediately before discharge
The Correct Answer is C
Choice A Reason: This is incorrect because administering Rho(D) immune globulin 24 hours before delivery is too early and may not provide adequate protection for the fetus. Administering it 24 hours after delivery is too late and may not prevent the mother from developing antibodies against the fetal Rh-positive blood cells.
Choice B Reason: This is incorrect because administering Rho(D) immune globulin in the first trimester is unnecessary and may not be effective, as the risk of Rh isoimmunization is very low before 28 weeks of gestation. Administering it within 2 hours of delivery is appropriate, but not sufficient, as it should be repeated within 72 hours after delivery.
Choice C Reason: This is correct because administering Rho(D) immune globulin at 28 weeks gestation and again within 72 hours after delivery is the recommended schedule for preventing Rh isoimmunization in Rh-negative pregnant women who have Rh-positive partners. This regimen can prevent up to 99% of cases of Rh isoimmunization by blocking the maternal immune response to the fetal Rh-positive blood cells.
Choice D Reason: This is incorrect because administering Rho(D) immune globulin at 32 weeks gestation is too late and may not prevent Rh isoimmunization if there has been any fetal-maternal hemorrhage before that time. Administering it immediately before discharge is also too late and may not prevent the mother from developing antibodies against the fetal Rh-positive blood cells.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A Reason: This is incorrect because sickle-cell anemia is a genetic disorder that affects the shape and function of the red blood cells. It is not related to the AFP level, which is a protein produced by the fetal liver and yolk sac.
Choice B Reason: This is incorrect because cardiac defects are abnormalities in the structure or function of the heart. They are not related to the AFP level, which is a marker of neural tube defects and abdominal wall defects.
Choice C Reason: This is correct because Down syndrome is a chromosomal disorder that results from an extra copy of chromosome 21. It is associated with a decreased AFP level, as well as increased levels of human chorionic gonadotropin (hCG) and unconjugated estriol (uE3).
Choice D Reason: This is incorrect because respiratory disorders are problems that affect the lungs and breathing. They are not related to the AFP level, which reflects the fetal development and integrity.
Correct Answer is C
Explanation
Choice A Reason: This is incorrect because it adds 10 months and 7 days to the last menstrual period, which is not Nägele's rule.
Choice B Reason: This is incorrect because it adds 9 months and 7 days to the last menstrual period, which is not Nägele's rule.
Choice C Reason: This is correct because it follows Nägele's rule, which is to subtract 3 months and add 7 days to the last menstrual period.
Choice D Reason: This is incorrect because it subtracts 4 months and adds 7 days to the last menstrual period, which is not Nägele's rule.
Choice E Reason: This is incorrect because it subtracts 4 months and adds 17 days to the last menstrual period, which is not Nägele's rule.

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