Knowing a drug's half-life enables the physician to determine the:
Peak plasma level.
Onset of action.
Schedule for repeated doses to maintain the drug level over 24 hours.
Duration of effectiveness.
The Correct Answer is C
Choice A rationale
The peak plasma level represents the maximum concentration of a drug achieved in the bloodstream after administration. While half-life influences the time to reach steady state, it does not directly determine the magnitude of the peak plasma level, which is more dependent on dose, absorption rate, and distribution volume.
Choice B rationale
Onset of action refers to the time it takes for a drug to exert its therapeutic effects after administration. While related to pharmacokinetic properties, the half-life primarily dictates the duration of drug presence and accumulation, not the immediate time to initial effect, which is more influenced by absorption and distribution.
Choice C rationale
A drug's half-life is the time it takes for the plasma concentration of a drug to be reduced by 50%. This pharmacokinetic parameter is critical for determining appropriate dosing intervals to maintain therapeutic drug levels within a desired range over a 24-hour period, preventing accumulation or sub-therapeutic concentrations.
Choice D rationale
The duration of effectiveness refers to the length of time a drug produces its therapeutic effect. While the half-life influences how long a drug remains in the system, the duration of effectiveness is also dependent on the drug's mechanism of action, receptor binding, and the patient's individual physiological responses, not solely on half-life.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale
Avoiding palpation of tender areas completely would be an incomplete assessment. While direct, forceful palpation of an acutely tender area should be approached cautiously, it is essential to gently assess the area's boundaries, consistency, and the presence of rebound tenderness or guarding to gather crucial diagnostic information.
Choice B rationale
Examining the tender area first in an abdominal assessment can cause significant pain and muscle guarding, making it difficult to assess other quadrants effectively and potentially skewing the assessment findings. This approach can also reduce patient cooperation for the remainder of the examination.
Choice C rationale
Auscultation for bowel sounds typically precedes palpation in an abdominal assessment because palpation can alter bowel motility and therefore the character of bowel sounds. While palpating the tender area last is correct, performing auscultation after palpation would introduce an artifact.
Choice D rationale
Examining the tender area last is the correct technique during an abdominal assessment. This approach minimizes patient discomfort, allows for a more thorough and accurate assessment of the non-tender areas first, and helps to establish rapport before eliciting potential pain, thereby ensuring a more reliable and complete examination.
Correct Answer is C
Explanation
Choice A rationale
Albuterol is a selective beta-2 adrenergic agonist. Its primary action is bronchodilation by stimulating beta-2 receptors in the bronchial smooth muscle, leading to relaxation and widening of the airways. It does not directly suppress the cough reflex, which is a protective mechanism to clear airways. Cough suppression is typically achieved by antitussive medications acting on the central nervous system or peripheral cough receptors.
Choice B rationale
Albuterol is a short-acting beta-agonist (SABA), characterized by a rapid onset of action and relatively short duration (4-6 hours). Therefore, it is used for immediate relief of bronchospasm and acute symptoms of asthma, not for long-term daily maintenance. Long-term maintenance medications include inhaled corticosteroids or long-acting beta-agonists (LABAs) used consistently to control inflammation and prevent exacerbations.
Choice C rationale
Albuterol's rapid onset of action and potent bronchodilatory effects make it the ideal medication for acute relief of bronchospasm in asthma. It is used as a "rescue" inhaler to quickly open airways during an asthma attack or before exercise to prevent exercise-induced bronchospasm. This immediate effect is crucial for alleviating respiratory distress.
Choice D rationale
Post-tussive emesis, or vomiting after coughing, is often a symptom of severe coughing spells. While albuterol can alleviate coughing by reducing bronchospasm, its primary mechanism is not to prevent emesis directly. Emesis is a gastrointestinal reflex; albuterol's action is primarily on the respiratory system. Addressing the underlying cause of severe coughing would indirectly reduce emesis.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.