The healthcare provider prescribes propylthiouracil (PTU) and Lugol’s solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?
Administer iodine one hour before PTU.
Schedule both medications at bedtime.
Administer both drugs together with a meal.
Give parenteral dose once every 24 hours.
The Correct Answer is A
Choice A reason:
Administering iodine one hour before PTU is recommended because iodine can help reduce the thyroid hormone levels more effectively when given before PTU. This sequence ensures that the iodine is absorbed and utilized by the thyroid gland before PTU inhibits the synthesis of new thyroid hormones.

Choice B reason:
Scheduling both medications at bedtime is not appropriate. PTU and iodine solutions should be administered at specific times to maximize their effectiveness. PTU is typically given in divided doses throughout the day, while iodine solutions are often given before meals.
Choice C reason:
Administering both drugs together with a meal is incorrect. PTU should be taken on an empty stomach to ensure proper absorption, and iodine solutions are usually given before meals.
Choice D reason:
Giving a parenteral dose once every 24 hours is not applicable for these medications. PTU is administered orally in divided doses, and iodine solutions are also given orally.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A Reason:
Bronchitis is a condition that affects the respiratory system, and while it is important to monitor, it is not a primary concern when administering phenylephrine. Phenylephrine is a decongestant that works by narrowing the blood vessels in the nasal passages, which can help relieve congestion but does not directly impact bronchitis.
Choice B Reason:
Diarrhea is a gastrointestinal condition that, while uncomfortable, does not significantly interact with phenylephrine. It is important to manage and monitor, but it does not pose a direct risk when taking phenylephrine.
Choice C Reason:
Hypertension is a significant concern when administering phenylephrine. Phenylephrine can increase blood pressure by causing vasoconstriction. For clients with hypertension, this can exacerbate their condition and lead to serious cardiovascular complications. Therefore, it is crucial to report this condition to the healthcare provider before administering the medication.

Choice D Reason:
Edema, or swelling, can be a symptom of various underlying conditions, including heart failure or kidney issues. While it is important to monitor, it is not as directly impacted by phenylephrine as hypertension. However, any underlying condition causing edema should be considered when administering medications.
Correct Answer is C
Explanation
Choice A Reason:
Avoiding taking the medication on an empty stomach is important to reduce gastrointestinal upset. Lithium can cause stomach irritation, and taking it with food can help mitigate this side effect. However, while this is good advice, it is not the most critical instruction to emphasize.
Choice B Reason:
Reporting fluctuations in weight to the healthcare provider is essential because significant weight changes can indicate potential side effects or complications from lithium therapy. Weight gain or loss can be a sign of thyroid dysfunction or other metabolic issues. While important, it is not the primary instruction to emphasize.
Choice C Reason:
Maintaining a fluid intake of 1500 to 2000 mL per day is crucial for clients taking lithium. Lithium levels in the blood can be affected by fluid balance, and dehydration can lead to lithium toxicity. Ensuring adequate hydration helps maintain stable lithium levels and reduces the risk of toxicity. This is the most critical instruction to emphasize to ensure the client’s safety and effective management of their condition.
Choice D Reason:
Keeping medication fliers for frequent review and reference is helpful for understanding the medication and its potential side effects. However, it is not the most critical instruction. The primary focus should be on maintaining proper hydration to prevent lithium toxicity.
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