The drug nalbuphine is an agonist-antagonist (partial agonist). The nurse understands that which is a characteristic of partial agonists?
They have a lower dependency potential than agonists.
They have a higher potency than agonists
They have anti-inflammatory effects.
They are given to reverse the effects of opiates
The Correct Answer is A
A. Partial agonists like nalbuphine have a lower dependency potential than full agonists. This means they are less likely to lead to physical dependence or tolerance when used for pain
management.
B. Partial agonists do not necessarily have a higher potency than agonists. Potency refers to the dose of a drug required to produce a specific effect, which can vary among different drugs regardless of their classification as agonists or partial agonists.
C. Partial agonists like nalbuphine are not typically used for their anti-inflammatory effects.
They are primarily used for pain management.
D. Partial agonists like nalbuphine are not typically used to reverse the effects of opiates. They may be used in certain situations to manage opioid-induced side effects or in cases of opioid overdose, but their primary indication is for pain management.
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Related Questions
Correct Answer is ["A","D","E"]
Explanation
A. Oral contraceptives: Phenobarbital can decrease the effectiveness of oral contraceptives, increasing the risk of contraceptive failure and unintended pregnancy.
B. Antihistamines: While phenobarbital can induce hepatic enzymes, leading to increased
metabolism of some antihistamines, this interaction is less clinically significant compared to the interactions with oral contraceptives, opioids, and diuretics.
C. Warfarin: Phenobarbital can induce the metabolism of warfarin, potentially reducing its anticoagulant effects and necessitating closer monitoring of international normalized ratio (INR) levels.
D. Opioids: Phenobarbital can increase the metabolism of opioids, leading to reduced analgesic effects and potentially causing inadequate pain control.
E. Diuretics: Phenobarbital can accelerate the metabolism of diuretics, potentially reducing their efficacy and necessitating adjustments in dosage or monitoring of electrolyte levels.
Correct Answer is B
Explanation
A. A lithium level of 0.9 mEq/L falls within the therapeutic range for lithium, so it is not too low.
B. A lithium level of 0.9 mEq/L is within the therapeutic range for lithium maintenance therapy, which typically ranges from 0.6 to 1.2 mEq/L. Therefore, it is considered therapeutic.
C. Lithium is commonly monitored with blood levels to ensure therapeutic efficacy and to prevent toxicity.
D. A lithium level of 0.9 mEq/L is not too high; it is within the therapeutic range.
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