The drug nalbuphine is an agonist-antagonist (partial agonist). The nurse understands that which is a characteristic of partial agonists?
They have a lower dependency potential than agonists.
They have a higher potency than agonists
They have anti-inflammatory effects.
They are given to reverse the effects of opiates
The Correct Answer is A
A. Partial agonists like nalbuphine have a lower dependency potential than full agonists. This means they are less likely to lead to physical dependence or tolerance when used for pain
management.
B. Partial agonists do not necessarily have a higher potency than agonists. Potency refers to the dose of a drug required to produce a specific effect, which can vary among different drugs regardless of their classification as agonists or partial agonists.
C. Partial agonists like nalbuphine are not typically used for their anti-inflammatory effects.
They are primarily used for pain management.
D. Partial agonists like nalbuphine are not typically used to reverse the effects of opiates. They may be used in certain situations to manage opioid-induced side effects or in cases of opioid overdose, but their primary indication is for pain management.
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Related Questions
Correct Answer is B
Explanation
A. Dobutamine is a sympathomimetic drug used to increase cardiac output in conditions such as heart failure. It is not an antidote for cholinergic drug overdose.
B. Atropine sulfate is the antidote for cholinergic drug overdose. It acts as a competitive antagonist to acetylcholine at muscarinic receptors, counteracting the effects of excessive cholinergic stimulation.
C. Atenolol is a beta-blocker used to manage hypertension and certain cardiac conditions. It is not an antidote for cholinergic drug overdose.
D. Bethanechol is a cholinergic agonist used to stimulate bladder contractions in urinary retention. It is not an antidote for cholinergic drug overdose; in fact, it would exacerbate cholinergic effects.
Correct Answer is B
Explanation
A. Bupropion is primarily used as an antidepressant and smoking cessation aid. It is not typically used for opioid withdrawal.
B. Methadone is a synthetic opioid agonist commonly used in the management of opioid withdrawal. It helps to alleviate withdrawal symptoms and can be used as part of a long-term maintenance program for opioid dependence.
C. Disulfiram is used in the treatment of alcohol dependence by creating unpleasant effects when alcohol is consumed. It is not indicated for opioid withdrawal.
D. Phenobarbital is a barbiturate with sedative and anticonvulsant properties. While it can be used to manage certain withdrawal symptoms, such as seizures associated with alcohol withdrawal, it is not typically used as a first-line treatment for opioid withdrawal.
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