The drug nalbuphine is an agonist-antagonist (partial agonist). The nurse understands that which is a characteristic of partial agonists?
They have a lower dependency potential than agonists.
They have a higher potency than agonists
They have anti-inflammatory effects.
They are given to reverse the effects of opiates
The Correct Answer is A
A. Partial agonists like nalbuphine have a lower dependency potential than full agonists. This means they are less likely to lead to physical dependence or tolerance when used for pain
management.
B. Partial agonists do not necessarily have a higher potency than agonists. Potency refers to the dose of a drug required to produce a specific effect, which can vary among different drugs regardless of their classification as agonists or partial agonists.
C. Partial agonists like nalbuphine are not typically used for their anti-inflammatory effects.
They are primarily used for pain management.
D. Partial agonists like nalbuphine are not typically used to reverse the effects of opiates. They may be used in certain situations to manage opioid-induced side effects or in cases of opioid overdose, but their primary indication is for pain management.
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Related Questions
Correct Answer is A
Explanation
A. Carbidopa prevents the breakdown of levodopa in the periphery, specifically in the gastrointestinal tract and peripheral tissues, allowing more levodopa to reach the brain and be converted to dopamine. This enhances the effectiveness of levodopa therapy in managing the symptoms of Parkinson's disease.
B. Carbidopa is not the biologic precursor of dopamine. It is a peripheral decarboxylase inhibitor that does not cross the blood-brain barrier.
C. Carbidopa does not directly allow for larger doses of levodopa to be given. However, by
inhibiting the peripheral breakdown of levodopa, it enhances the availability of levodopa to the central nervous system, potentially improving therapeutic efficacy.
D. While levodopa-carbidopa combination therapy may have fewer drug-food interactions compared to levodopa alone, the primary reason for combining these medications is to enhance the effectiveness of levodopa by preventing its peripheral breakdown.
Correct Answer is C
Explanation
A. The 21-year-old patient who has never had surgery before: While lack of previous surgery experience may contribute to anxiety, it doesn't inherently increase the risk of altered response to anesthesia.
B. The 40-year-old patient who is to have kidney stone removed: While the type of surgery may influence anesthesia considerations, being 40 years old alone doesn't significantly increase the risk of altered response to anesthesia.
C. The 82-year-old patient who is to have gallbladder removal: Advanced age is a significant risk factor for altered response to anesthesia due to age-related changes in physiology, metabolism, and drug clearance.
D. The 35-year-old patient who stopped smoking 8 years ago: While smoking history can impact anesthesia considerations, stopping smoking 8 years ago likely reduces the associated risks compared to current smokers.
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