The healthcare provider prescribes propylthiouracil (PTU) and Lugol’s solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?

Schedule both medications at bedtime.

Administer iodine one hour before PTU.

Give parental dose once every 24 hours.

Offer both drugs together with a meal.

Answer and Explanation

The Correct Answer is B

A) Schedule both medications at bedtime:
Administering both medications at bedtime may not be the most appropriate schedule. PTU is typically administered multiple times a day to maintain consistent therapeutic levels in the bloodstream. Additionally, administering Lugol’s solution at bedtime may not provide sufficient time for the iodine to take effect before the PTU.

B) Administer iodine one hour before PTU:
This option is correct. Lugol’s solution, a strong iodine solution, is often given before antithyroid medications such as PTU or methimazole to temporarily block thyroid hormone production. Administering iodine about one hour before PTU allows the iodine to be taken up by the thyroid gland, effectively reducing thyroid hormone synthesis before the PTU starts to inhibit the conversion of T4 to T3.

C) Give parental dose once every 24 hours:
This option does not address the timing of administration between PTU and Lugol’s solution. While it may be correct for the dosing frequency of PTU, it does not specify when to administer Lugol’s solution in relation to PTU.

D) Offer both drugs together with a meal:
Administering both drugs together with a meal may not be appropriate, especially considering that Lugol’s solution needs to be absorbed into the bloodstream to exert its effect on the thyroid gland. Administering Lugol’s solution and PTU together may not allow adequate time for the iodine to take effect before the PTU starts to inhibit thyroid hormone production.

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Correct Answer is D

Explanation

A) Keep medication refrigerated:
Metronidazole tablets do not typically require refrigeration. Storing the medication at room temperature is usually sufficient. Refrigeration may not be necessary and could potentially lead to confusion or unnecessary inconvenience for the client.

B) Drink a liter of water daily:
While maintaining hydration is generally important for overall health, there's no specific requirement to drink a liter of water daily solely because of metronidazole therapy. However, encouraging adequate fluid intake is beneficial to prevent dehydration, especially if diarrhea is present due to Clostridium difficile infection.

C) Take one hour after eating:
Metronidazole can be taken with or without food. It's generally well tolerated with food to reduce gastrointestinal side effects such as nausea. However, taking it with food or on an empty stomach does not significantly affect its effectiveness.

D) Avoid the use of alcohol:
This is the correct answer. Consuming alcohol while taking metronidazole can lead to a disulfiram-like reaction, characterized by symptoms such as flushing, headache, nausea, vomiting, and abdominal cramps. This reaction occurs because metronidazole inhibits the breakdown of acetaldehyde, leading to its accumulation in the body when alcohol is consumed. Therefore, it's crucial to advise clients to abstain from alcohol during metronidazole therapy and for at least 48 hours after completing the course of treatment.

A. Monitor for any signs of sexual dysfunction. B. Decrease cigarette use to a pack per day. C. Notify the healthcare provider of lethargy. D. Take the medication an hour after antacids.

Correct Answer is B

Explanation

A) Monitoring blood pressure: Tamsulosin is an alpha-adrenergic blocker used to relax the muscles in the prostate and bladder neck, improving urinary flow in benign prostatic hyperplasia (BPH). Monitoring blood pressure is important because tamsulosin can cause orthostatic hypotension, especially when starting the medication or increasing the dose.
B) Assessing urine output: This is the correct answer. Tamsulosin can cause urinary retention, especially in patients with bladder outlet obstruction. Monitoring urine output helps assess for any signs of urinary retention or decreased urinary flow.
C) Obtaining daily weights: This is not typically necessary for monitoring the effects of tamsulosin. Changes in weight may occur due to other factors and are not directly related to the medication.
D) Performing a bladder scan: While performing a bladder scan may be indicated if there are specific concerns about urinary retention, assessing urine output is a more direct and immediate way to monitor for this adverse reaction.

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The healthcare provider prescribes propylthiouracil (PTU) and Lugol’s solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?

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