The nurse is administering insulin lispro (Humalog) and will keep in mind that this insulin will start to have an effect within which time frame?
15 minutes.
1 to 2 hours.
80 minutes.
3 to 5 hours.
The Correct Answer is A
Choice A rationale: Insulin lispro (Humalog) is a rapid-acting insulin analog. Its amino acid sequence has been modified to allow for rapid absorption from the injection site into the bloodstream. This modification prevents the formation of hexamers, which are slowly absorbed, allowing the insulin to become biologically active within 15 minutes of administration.
Choice B rationale: Regular insulin, a short-acting type, typically has an onset of action of 30 to 60 minutes. Intermediate-acting insulins like NPH have a much longer onset, starting around 1 to 2 hours. Insulin lispro's rapid action is designed to be taken with meals to control postprandial hyperglycemia, which begins immediately after eating.
Choice C rationale: An onset of 80 minutes falls outside the typical time frame for both rapid and short-acting insulins. The pharmacokinetics of insulin lispro are specifically engineered for a quick onset to coincide with mealtime glucose spikes, and its action is not delayed for over an hour.
Choice D rationale: The peak effect of insulin lispro is around 1 to 2 hours, but its onset is much faster. Long-acting insulins like glargine (Lantus) have a much more prolonged effect, with a duration that can extend to 24 hours, but they lack a distinct peak. The 3 to 5 hour period is too long for the onset of a rapid-acting insulin.
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Related Questions
Correct Answer is B
Explanation
Choice A rationale: This statement is incorrect. Insulin can and is administered intravenously in specific clinical situations, particularly for managing diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS). Intravenous administration allows for rapid and precise titration of insulin dosage to achieve stable blood glucose levels.
Choice B rationale: Regular insulin is the only type of insulin that can be administered intravenously. Its short duration of action and predictable profile make it ideal for titrating doses in a controlled hospital setting. Other types of insulin, such as rapid-acting or long-acting analogs, are not formulated for intravenous use and carry a risk of unpredictable effects.
Choice C rationale: Insulin aspart and insulin lispro are rapid-acting insulins designed for subcutaneous administration. They are not approved or recommended for intravenous use due to their formulation and the potential for dose-response unpredictability. There is no established protocol for administering these insulins intravenously, even with a dose reduction.
Choice D rationale: While intravenous insulin is often used in emergent situations like DKA or HHS, it is not limited to emergencies. It may also be used in other controlled settings, such as during surgery or in critical care, to manage hyperglycemia. Its use is based on the need for tight glycemic control rather than just emergency status.
Correct Answer is A
Explanation
Choice A rationale: For a young adult with newly diagnosed type 1 diabetes mellitus, annual eye examinations by an ophthalmologist are recommended starting five years after the diagnosis. The risk of diabetic retinopathy, a microvascular complication, increases over time with chronic hyperglycemia. Therefore, maintaining a regular schedule for eye exams is crucial for early detection and management of vision changes.
Choice B rationale: This statement is incorrect as it suggests waiting for a vision problem to develop or until a later age. Regular, proactive screening is essential for managing diabetes. Diabetic retinopathy often progresses without noticeable symptoms in its early stages, so waiting for a change in vision can lead to delayed treatment and more significant damage.
Choice C rationale: This statement is inaccurate because while vision can be affected, it does not necessarily change quickly in the early stages. The recommendation for annual or even more frequent exams is based on the duration of diabetes and the presence of any complications, not an assumption of rapid change. For a newly diagnosed client, the standard is annual exams after a few years.
Choice D rationale: This statement is dangerously incorrect. Chronic hyperglycemia is a major risk factor for several eye diseases, including diabetic retinopathy, cataracts, and glaucoma. All clients with diabetes, regardless of age or how well-controlled their blood sugar is, are at risk for these complications and require regular, scheduled eye examinations to monitor for early signs of damage.
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