The nurse is reviewing the medication orders for a patient who will be receiving aminoglycoside therapy.
Which other medication or medication class, if ordered, would be a potential interaction concern?

Proton pump inhibitors

Calcium channel blockers

Loop diuretics

Phenytoin

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Proton pump inhibitors (PPIs) are used extensively for the treatment of gastric acid-related disorders, often over the long term, which raises the potential for clinically significant drug interactions in patients receiving concomitant medications.

However, there is no specific mention of a significant interaction between PPIs and aminoglycosides.

Choice B rationale:

Aminoglycoside antibiotics and calcium channel blockers can interact at the neuromuscular junctions. This interaction is of clinical significance because when these agents are given concurrently during the perioperative period they may lead to respiratory depression or prolonged apnea. However, this is not directly related to the therapeutic effect of aminoglycosides, but rather a side effect of their combined use.

Choice C rationale:

The loop-diuretics (ethacrynic acid, furosemide, bumetamide) and aminoglycoside antibiotics (kanamycin, gentamicin, tobramycin, amikacin, etc.) are important drugs frequently used to treat seriously ill patients. Not uncommonly both types of drugs are given to the same patient exposing that patient to the risk of a hearing loss (ototoxicity)5. In addition, the risk of ototoxicity could be enhanced by the concomitant use of loop diuretics and aminoglycoside antibiotics.

Choice D rationale:

Phenytoin is a medication used to treat seizures. It has a complex pharmacokinetic profile and can interact with many other drugs. However, there is no specific mention of a significant interaction between phenytoin and aminoglycosides.

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Correct Answer is B

Explanation

Choice A rationale:

Macrolides Macrolides, such as erythromycin and azithromycin, are a class of antibiotics that are typically used to treat infections caused by gram-positive bacteria and some respiratory tract infections. They are not the first line of treatment for urinary tract infections.

Choice B rationale:

Sulfonamides Sulfonamides, such as sulfamethoxazole, are often used to treat urinary tract infections. They work by stopping the growth of bacteria. Sulfonamides are often combined with other antibiotics like trimethoprim to increase their effectiveness. This combination is commonly known as co-trimoxazole.

Choice C rationale:

Carbapenems Carbapenems are a class of antibiotics that are usually reserved for serious infections caused by gram-negative bacteria. While they can be used to treat a variety of infections, they are not typically the first choice for urinary tract infections.

Choice D rationale:

Tetracyclines Tetracyclines are a group of broad-spectrum antibiotics that are effective against a wide range of bacteria. However, they are not typically used for urinary tract infections. They are more commonly used for infections such as acne, chlamydia, and Lyme disease.

Please consult with a healthcare professional for accurate information.

A. Polyuria B. Sweating C. Tachycardia D. Blurry vision

Correct Answer is ["B","C","D"]

Explanation

Choice A rationale:

Polyuria, which is frequent or excessive urination, is not typically a symptom of hypoglycemia. It is more commonly associated with hyperglycemia, or high blood sugar levels.

Choice B rationale:

Sweating is indeed a common symptom of hypoglycemia. When blood sugar levels fall too low, the body may respond by sweating as it releases adrenaline in response to the hypoglycemic state.

Choice C rationale:

Tachycardia, or a fast heartbeat, is another common symptom of hypoglycemia. This is part of the body’s response to low blood sugar levels, as it releases adrenaline to try to raise these levels.

Choice D rationale:

Blurry vision can be a symptom of hypoglycemia. When blood sugar levels fall, it can affect the ability of the eyes to focus, leading to blurry vision.

Choice E rationale:

Polydipsia, or excessive thirst, is not typically a symptom of hypoglycemia. Like polyuria, it is more commonly associated with hyperglycemia.

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The nurse is reviewing the medication orders for a patient who will be receiving aminoglycoside therapy. Which other medication or medication class, if ordered, would be a potential interaction concern?

Nursing Test Bank

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A patient has a urinary tract infection. The nurse knows that which class of drugs is especially useful for such infections?

Correct Answer is B

Explanation

A nurse is reinforcing teaching with a client who has type 2 diabetes mellitus. The nurse determines that teaching has been effective when the client identifies which of the following manifestations of hypoglycemia? (Select all that apply.)

Correct Answer is ["B","C","D"]

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The nurse is reviewing the medication orders for a patient who will be receiving aminoglycoside therapy.
Which other medication or medication class, if ordered, would be a potential interaction concern?