The nurse is reviewing the medication orders for a patient who will be receiving aminoglycoside therapy.
Which other medication or medication class, if ordered, would be a potential interaction concern?

Choice A rationale:

Aspirin is known as a salicylate and a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking a certain natural substance in your body to reduce pain and swelling. However, one of the key reasons aspirin is administered to a patient with a history of myocardial infarction (MI) is due to its antiplatelet aggregate properties. This effect reduces the risk of stroke and heart attack. If a patient has recently had surgery on clogged arteries (such as bypass surgery, carotid endarterectomy, coronary stent), doctors may direct them to use aspirin in low doses as a “blood thinner” to prevent blood clots.

Choice B rationale:

While aspirin does have analgesic properties, meaning it can relieve mild to moderate pain from conditions such as muscle aches, toothaches, common cold, and headaches, this is not the primary reason it would be administered to a patient with a history of MI. The main goal in this context is to prevent further cardiac events, which is achieved through aspirin’s antiplatelet effects.

Choice C rationale:

Aspirin does have anti-inflammatory properties and it may be used to reduce pain and swelling in conditions such as arthritis. However, in the context of a patient with a history of MI, the anti-inflammatory property is not the primary reason for administering aspirin. The key purpose is to leverage its antiplatelet effects to prevent further cardiac events.

Choice D rationale:

Aspirin can be used to reduce fever, which is what the term ‘antipyretic’ refers to. However, similar to the analgesic and antiinflammatory properties, the antipyretic property is not the primary reason for administering aspirin to a patient with a history of MI. The main goal is to prevent further cardiac events through its antiplatelet effects.

Choice A rationale:

While it’s important for the client’s family to be aware of the disease and take precautions, they do not necessarily need to take medications to prevent infection. Tuberculosis (TB) is a contagious disease, but it typically requires close and prolonged contact to spread. Family members should be tested for TB, and if they test positive, then treatment would be necessary.

Choice B rationale:

This is the correct answer. A typical course of treatment for TB involves 6 to 9 months of consistent medication use. This is because TB bacteria die very slowly, and medications need to be taken for several months to ensure that all the bacteria are killed. If treatment is stopped too soon, some bacteria may survive and become resistant to the drugs.

Choice C rationale:

It’s not accurate to say that medications will need to be taken for the rest of the client’s life. While TB treatment is lengthy, it does not continue indefinitely. Once the full course of treatment is completed and the disease is cured, further medication is not typically necessary.

Choice D rationale:

The Mantoux test, also known as the tuberculin skin test, is used to determine whether a person has TB infection. However, the test can remain positive for a long time, even after successful treatment. Therefore, medications should not be taken until the Mantoux test is negative. Instead, the duration of treatment is determined by the healthcare provider based on various factors, including the patient’s response to the medication.