The nurse provides care for a patient with an 8-year history of Parkinson's disease. The patient has difficulty getting out of chairs, makes tremulous movements, and mumbles words. What is the best explanation for these clinical manifestations?
Thrombosis of the small blood vessels in the substantia nigra.
Increased acetylcholine levels and cholinergic activity in the brain.
Cell-mediated immune response and muscle fiber damage.
Increased production of dopamine in the motor cortex.
The Correct Answer is A
Choice A:
Thrombosis of the small blood vessels in the substantia nigra is the best explanation for the clinical manifestations observed in the patient. The substantia nigra is an area in the brain responsible for producing dopamine, a neurotransmitter involved in motor control. Thrombosis, or the formation of blood clots, in the small blood vessels of the substantia nigra can lead to a decrease in dopamine production, resulting in the symptoms of Parkinson's disease.
Choice B:
Increased acetylcholine levels and cholinergic activity in the brain are not the primary factors causing the manifestations of Parkinson's disease. In fact, Parkinson's disease is characterized by a decrease in dopamine levels, not an increase in acetylcholine.
Choice C:
Cell-mediated immune response and muscle fiber damage are not the main mechanisms underlying the clinical manifestations of Parkinson's disease. While inflammation and immune responses may play a role in the progression of the disease, they are not the primary cause of the symptoms observed.
Choice D:
Increased production of dopamine in the motor cortex is not the cause of the symptoms in Parkinson's disease. In fact, patients with Parkinson's disease experience a decrease in dopamine production due to the degeneration of dopamine-producing neurons in the substantia nigra.
Overall, the most plausible explanation for the patient's clinical manifestations is thrombosis of the small blood vessels in the substantia nigra, leading to a decrease in dopamine production.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: "Are you experiencing any nausea at this time?" is not the highest priority question because it is a common side effect of anesthesia, which is usually given during a thyroidectomy. Nausea is not a life-threatening complication, and it usually resolves within a few days after surgery.
Choice B reason: "Have you noticed any decrease in muscle weakness?" is not the highest priority question because it is a sign of improvement in the client's condition. A subtotal thyroidectomy is a surgical procedure that removes part of the thyroid gland, which is responsible for producing hormones that regulate the metabolism, growth, and development of the body. A client who has a thyroidectomy may have hypothyroidism, which is a condition where the thyroid gland does not produce enough hormones, causing symptoms such as fatigue, weight gain, and muscle weakness. A decrease in muscle weakness indicates that the client is responding well to the hormone replacement therapy, which is usually given after a thyroidectomy.
Choice C reason: "Do you have any numbness or tingling of your hands?" is the highest priority question because it is a sign of a possible complication of a thyroidectomy, which is hypocalcemia. Hypocalcemia is a condition where the blood has a low level of calcium, which is an electrolyte that helps regulate the nerve and muscle function, including the heart. A thyroidectomy can cause hypocalcemia if the parathyroid glands, which are small glands that are located behind the thyroid gland and produce a hormone that regulates the calcium level in the blood, are accidentally damaged or removed during the surgery. Hypocalcemia can cause symptoms such as numbness and tingling of the hands, feet, and lips, muscle spasms, seizures, and cardiac arrhythmias, which can be fatal if not treated promptly.
Choice D reason: "Do you have any breathing difficulties while walking?" is not the highest priority question because it is a sign of a possible complication of a thyroidectomy, which is tracheal compression. Tracheal compression is a condition where the trachea, which is the airway that connects the mouth and nose to the lungs, is squeezed or narrowed by the swelling or bleeding of the tissues around the thyroid gland. Tracheal compression can cause symptoms such as difficulty breathing, hoarseness, stridor, and cyanosis, which can be life-threatening if not treated promptly. However, tracheal compression is more likely to occur immediately after surgery, not 48 hours later.
Correct Answer is C
Explanation
Choice A reason: Enlargement of the spleen is not a common sign of non-Hodgkin lymphoma, but it may occur in some cases. It is more likely to be associated with chronic lymphocytic leukemia or Hodgkin lymphoma.
Choice B reason: Confusion and agitation are not typical symptoms of non-Hodgkin lymphoma, but they may indicate central nervous system involvement or metabolic disturbances. They are more common in patients with brain tumors or infections.
Choice C reason: Frequent respiratory infections are a possible manifestation of non-Hodgkin lymphoma, as the disease affects the immune system and makes the client more susceptible to infections. The respiratory tract is one of the most common sites of infection in patients with non-Hodgkin lymphoma.
Choice D reason: Painful lesions of the lips and oral mucosa are not characteristic of non-Hodgkin lymphoma, but they may be caused by other conditions such as herpes simplex virus, aphthous ulcers, or oral cancer. They are more common in patients with immunodeficiency or poor oral hygiene.
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