The nurse should recognize which response is the immune system’s reaction to a source of inflammation?
Decreased histamine production.
Vasoconstriction.
Increased vascular permeability.
Activation of exocytosis.
The Correct Answer is C
Choice A reason: Decreased histamine production does not occur during inflammation; histamine release increases, promoting vasodilation and permeability. Inflammation triggers immune responses, including histamine-mediated vascular changes to deliver immune cells. This choice is incorrect, as reduced histamine contradicts the immune system’s proinflammatory response to an inflammatory stimulus.
Choice B reason: Vasoconstriction reduces blood flow, counteracting inflammation’s goal of delivering immune cells to the site. Inflammation causes vasodilation to enhance blood flow and permeability. Vasoconstriction is not a primary immune response to inflammation, making this an incorrect choice for the body’s reaction to an inflammatory source.
Choice C reason: Increased vascular permeability is a hallmark of inflammation, allowing plasma, immune cells, and proteins to reach the affected site. Histamine and cytokines trigger this response, facilitating immune defense and tissue repair. This aligns with the immune system’s proinflammatory mechanism, making it the correct response to inflammation.
Choice D reason: Activation of exocytosis involves cellular vesicle release, not a primary inflammatory response. While immune cells may use exocytosis to release mediators, increased vascular permeability is the direct immune reaction to inflammation, enabling immune access. This choice is less specific, making it incorrect for the primary response.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Yellow sclera (jaundice) result from bilirubin accumulation in cirrhosis, not high ammonia levels. Ammonia toxicity affects the brain, causing neurological symptoms. While jaundice is common in cirrhosis, it is unrelated to ammonia, making this incorrect for the symptom linked to elevated serum ammonia.
Choice B reason: Shortness of breath on exertion may occur in cirrhosis due to ascites or hepatopulmonary syndrome, but it is not caused by high ammonia levels. Ammonia primarily affects the brain, leading to encephalopathy. This symptom is unrelated to ammonia toxicity, making it an incorrect choice.
Choice C reason: Impaired skin integrity may occur in cirrhosis from pruritus or edema, but it is not directly linked to high ammonia levels. Ammonia causes cerebral toxicity, manifesting as neurological changes. Skin issues are secondary complications, making this incorrect for the primary symptom of elevated ammonia.
Choice D reason: High serum ammonia in cirrhosis leads to hepatic encephalopathy, causing altered consciousness, from confusion to coma. Ammonia crosses the blood-brain barrier, disrupting neurotransmitter function and cerebral metabolism. This is the primary symptom of ammonia toxicity, aligning with cirrhosis’s neurological complications, per hepatology evidence.
Correct Answer is D
Explanation
Choice A reason: Decreased acetylcholine is not the primary cause of Parkinson’s disease. Parkinson’s results from dopamine loss in the substantia nigra, disrupting motor control. Acetylcholine imbalance may occur in other conditions like Alzheimer’s, but it is not the pathophysiological basis for Parkinson’s motor symptoms.
Choice B reason: Increased serotonin is not linked to Parkinson’s disease. Parkinson’s is caused by dopamine depletion in the basal ganglia, leading to motor dysfunction. Serotonin imbalances may affect mood, but they are not the core mechanism, making this incorrect for the disease’s pathophysiological basis.
Choice C reason: Disruption in the myelin sheath occurs in multiple sclerosis, not Parkinson’s. Parkinson’s involves neuronal loss in the substantia nigra, reducing dopamine. Myelin is unrelated to Parkinson’s motor symptoms, making this incorrect, as dopamine deficiency is the established pathophysiological mechanism driving the disease.
Choice D reason: Parkinson’s disease is caused by a diminished amount of dopamine due to degeneration of substantia nigra neurons. Dopamine deficiency disrupts basal ganglia function, causing tremors, rigidity, and bradykinesia. This is the core pathophysiological basis, supported by neurological evidence linking dopamine loss to Parkinson’s symptoms.
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