The student nurse learns that the process in which bilirubin is changed from a fat-soluble product to a water-soluble product is known as:
Unconjugation of bilirubin.
Albumin binding.
Enterohepatic circuit.
Conjugation of bilirubin.
The Correct Answer is D
Choice A rationale
Unconjugation of bilirubin is the process where bilirubin, initially produced in a water-insoluble form (unconjugated or indirect bilirubin), is not yet processed by the liver. This form cannot be easily excreted by the body.
Choice B rationale
Albumin binding refers to the transport of unconjugated bilirubin in the bloodstream. Because unconjugated bilirubin is fat-soluble and not easily dissolved in water, it binds to albumin, a protein in the blood, which allows it to be transported to the liver.
Choice C rationale
The enterohepatic circuit describes the circulation of bile acids from the liver to the small intestine, where they aid in fat digestion and absorption, and then back to the liver. Bilirubin is a byproduct of heme breakdown and is processed separately in the liver before excretion in bile.
Choice D rationale
Conjugation of bilirubin is the process that occurs in the liver where the enzyme uridine diphosphoglucuronate glucuronosyltransferase (UGT) attaches glucuronic acid molecules to unconjugated bilirubin. This process transforms the fat-soluble unconjugated bilirubin into a water-soluble form called conjugated (or direct) bilirubin, which can then be excreted in bile into the intestines.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Positioning the newborn supine on a radiant warmer is appropriate for maintaining thermoregulation. However, applying only a sterile gauze dressing to a large abdominal wall defect that is not covered by a membrane does not adequately protect the exposed organs from contamination, drying, or injury. This increases the risk of infection and fluid loss.
Choice B rationale
Placing the newborn into a sterile bowel bag up to the axilla is the recommended immediate action for an abdominal wall defect such as gastroschisis (protrusion without a membrane). The sterile bag helps to maintain a moist environment, prevent heat and fluid loss, and protect the exposed organs from trauma and contamination until surgical repair can be performed.
Choice C rationale
While breastfeeding promotes bonding and provides essential nutrients, it is not the priority action for a newborn with a large, uncovered abdominal wall defect immediately after birth. The immediate focus should be on protecting the exposed organs and stabilizing the newborn. Breastfeeding can be initiated once the newborn is stable and the abdominal defect is appropriately managed.
Choice D rationale
Providing intermittent suction via an orogastric tube may be necessary later to decompress the gastrointestinal system, but it is not the immediate priority for a newborn with a large, uncovered abdominal wall defect. The initial action should focus on protecting the exposed organs.
Correct Answer is C
Explanation
Choice A rationale
Limiting the newborn's intake of milk is contraindicated in the treatment of hyperbilirubinemia. Adequate hydration and frequent feedings are essential to promote bilirubin excretion through stool and urine. Decreased intake can exacerbate dehydration and worsen jaundice. Normal feeding frequency for newborns is typically every 2-3 hours.
Choice B rationale
Feeding the newborn every six hours is not an appropriate intervention for a jaundiced infant receiving phototherapy. Frequent feedings, typically every 2-3 hours, are necessary to promote bilirubin excretion. Prolonged intervals between feedings can lead to dehydration and hinder the effectiveness of phototherapy.
Choice C rationale
Turning the infant every two hours is a crucial nursing intervention during phototherapy. This ensures that all body surfaces are exposed to the ultraviolet light, maximizing the breakdown of bilirubin in the skin. Consistent exposure of all areas helps to lower bilirubin levels more effectively.
Choice D rationale
Applying an oil-based lotion to the newborn's skin during phototherapy is contraindicated. Oil-based lotions can create a barrier on the skin, reducing the penetration and effectiveness of the ultraviolet light. Only water-based lotions, if necessary, should be used sparingly and with caution, as some may absorb UV light.
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