Therapeutic management of most children with Hirschsprung's disease is primarily

The correct answer is choice A. Wearing cotton underpants.

Choice A rationale:

Wearing cotton underpants is the recommended option to prevent urinary tract infections (UTIs) in young girls. Cotton underpants allow better air circulation, which helps to keep the perineal area dry. This reduces the growth of bacteria and prevents moisture buildup, which are crucial in preventing UTIs. Synthetic fabrics can trap moisture and create a conducive environment for bacterial growth, increasing the risk of UTIs.

Choice B rationale:

Limiting bathing as much as possible is not an appropriate recommendation for preventing UTIs. Hygiene is essential to prevent UTIs, and regular bathing is part of maintaining cleanliness. Overly limiting bathing can lead to poor hygiene practices and may not significantly prevent UTIs, as they are often caused by factors beyond bathing frequency.

Choice C rationale:

Increasing fluids and decreasing salt intake can be beneficial for overall health but may not directly prevent UTIs. While staying hydrated is important for maintaining urinary health, simply increasing fluids and reducing salt intake might not be sufficient to prevent UTIs. Hygiene practices and proper perineal care play a more significant role in preventing UTIs.

Choice D rationale:

Cleansing the perineum with water after voiding is a good hygiene practice, but it alone may not be enough to prevent UTIs. While maintaining cleanliness is crucial, using water to cleanse the perineum after voiding should be combined with other practices, such as wearing cotton underpants and proper wiping techniques, to effectively prevent UTIs.

Choice A rationale:

Increased appetite is a common side effect of corticosteroid therapy. Corticosteroids are known to affect various metabolic processes, and one of the effects is an increase in appetite. This can lead to weight gain, especially when the increased calorie intake is not balanced by physical activity.

Choice B rationale:

Fever is not a typical side effect of corticosteroid therapy. Corticosteroids are often used to reduce inflammation and suppress the immune response, which can help in managing conditions like autoimmune diseases, allergies, and inflammatory disorders. Fever is not a direct result of corticosteroid administration.

Choice C rationale:

Weight loss is not a common side effect of corticosteroid therapy. In fact, corticosteroids are more likely to cause weight gain due to their influence on appetite, metabolism, and fluid retention.

Choice D rationale:

Hypertension (high blood pressure) can indeed be a side effect of corticosteroid therapy. Corticosteroids can lead to sodium and water retention, which can contribute to increased blood pressure, particularly in individuals who are already at risk for hypertension. However, among the options provided, increased appetite is a more directly associated side effect of corticosteroid therapy.