What clinical finding is associated with hydralazine toxicity?
Seizure
Hypertension
Tachycardia
Constipation
The Correct Answer is C
A. Seizure: Seizures are not a common manifestation of hydralazine toxicity. While severe hypotension could contribute to CNS symptoms, seizures are not a typical or expected clinical finding with this medication.
B. Hypertension: Hydralazine is a direct vasodilator used to lower blood pressure. Hypertension is not associated with hydralazine toxicity; instead, excessive hypotension may occur if the drug effect is too strong.
C. Tachycardia: Tachycardia is a common clinical finding associated with hydralazine toxicity. The vasodilation caused by hydralazine can lead to reflex sympathetic stimulation, resulting in an increased heart rate as the body attempts to maintain cardiac output and blood pressure.
D. Constipation: Constipation is not related to hydralazine use or toxicity. This adverse effect is not expected and does not indicate toxicity from the medication.
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Related Questions
Correct Answer is D
Explanation
A. Hold medication if heart rate is greater than 60 bpm: Beta-blockers are typically held if the heart rate is less than 60 bpm, not greater. Administering the medication when the heart rate is above 60 bpm is generally safe, so this instruction is inaccurate.
B. Report signs of liver damage, including dark-colored urine: While some medications can affect liver function, beta-blockers rarely cause liver toxicity. Monitoring for liver damage is not a standard teaching point for typical beta-blocker use unless the client has preexisting liver disease.
C. Stop taking this medication if you experience dizziness: Abruptly stopping beta-blockers can precipitate rebound hypertension or tachycardia, which can be dangerous. Clients should be instructed to notify their healthcare provider rather than independently discontinuing the medication.
D. Sexual dysfunction may occur with this medication: Beta-blockers can cause side effects such as erectile dysfunction or decreased libido. Educating the client about potential sexual side effects helps set expectations and encourages open discussion with the healthcare provider if symptoms develop.
Correct Answer is C
Explanation
A. Red blood cells: While red blood cell counts provide information about oxygen-carrying capacity and anemia, they do not directly reflect the anticoagulant effect of heparin or the risk of bleeding due to its use. Monitoring RBCs is not sufficient for safe heparin therapy.
B. International normalized ratio (INR): INR is primarily used to monitor warfarin therapy, not heparin. It measures the extrinsic pathway of coagulation, whereas heparin affects the intrinsic pathway, so INR is not the appropriate laboratory value for heparin monitoring.
C. Partial thromboplastin time (PTT): PTT measures the effectiveness of the intrinsic and common coagulation pathways, which are directly affected by heparin. Monitoring PTT helps ensure that the client maintains a therapeutic anticoagulation range and reduces the risk of bleeding or clot formation.
D. Hematocrit: Hematocrit reflects the proportion of red blood cells in the blood and can indicate blood loss over time. While important for general assessment, it does not specifically monitor heparin’s anticoagulant effect and is not the primary lab value to guide dosing.
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