What side effect should a client be aware of when prescribed diphenhydramine?

A. Client #1: A 45-year-old male with migraine, dehydration, and a history of hypertension could safely receive a calcium channel blocker if indicated for blood pressure management. No contraindications are present in his profile that would make the order unsafe.

B. Client #2: A 68-year-old with influenza and chronic stable angina may benefit from a calcium channel blocker to manage angina symptoms. There are no absolute contraindications based on his current condition or history.

C. Client #3: A 39-year-old post-spinal surgery with chronic hypertension could be prescribed a calcium channel blocker for blood pressure control. His surgical status does not contraindicate the use of this medication unless there are specific hemodynamic concerns.

D. Client #4: A 54-year-old with acute MI and a lisinopril allergy should raise concern because calcium channel blockers, particularly non-dihydropyridines (like verapamil or diltiazem), may interact with ACE inhibitors and affect cardiac function. Post-MI clients require careful selection of antihypertensive therapy.

A. A client needing stroke prevention: Antiplatelet therapy is indicated for clients at risk of ischemic stroke or recurrent stroke because it helps prevent platelet aggregation, reducing the likelihood of clot formation in the arteries. This intervention is especially beneficial in clients with a history of transient ischemic attacks or atherosclerotic cardiovascular disease.

B. A client with a vitamin K deficiency: Vitamin K deficiency primarily affects clotting factor synthesis, leading to a bleeding tendency. Antiplatelet therapy would increase the risk of bleeding in these clients, making it contraindicated rather than indicated.

C. A client with a low platelet count: Clients with thrombocytopenia are already at risk for bleeding, and antiplatelet therapy would further impair clot formation, increasing the potential for hemorrhage. It is therefore avoided in these situations.

D. A client diagnosed with leukemia: Leukemia can be associated with low platelet counts or abnormal platelet function, placing the client at risk for bleeding. Administering antiplatelet therapy could exacerbate hemorrhagic complications rather than provide benefit.